{"title":"Stimuli-Responsive Molecularly Imprinted Polymers: Mechanism and Applications","authors":"Zheng Li, Jiaming Deng, Peirong Ma, Haoran Bai, Yuting Jin, Yanling Zhang, Alideertu Dong, Munkhjargal Burenjargal","doi":"10.1002/jssc.202400441","DOIUrl":null,"url":null,"abstract":"<div>\n \n <p>Molecularly imprinted polymers (MIPs) are very suitable for extraction, drug delivery systems, and sensors due to their good selective adsorption ability, but the difficulty of eluting templates during synthesis and the limitation of application scenarios put higher demands on MIPs. Stimuli-responsive MIPs (SR-MIPs) can actively respond to changes in external conditions to realize various functions, which provides new ideas for the further development of MIPs. This paper reviews the multiple response modes of MIPs, including the common temperature, pH, photo, magnetic, redox-responsive and rare gas, biomolecule, ion, and solvent-responsive MIPs, and explains the mechanism, composition, and applications of such SR-MIPs. These SR-MIPs and the resulting dual/multiple-responsive MIPs have good selectivity, and controllability, and are very promising for isolation and extraction, targeted drug delivery, and electro-sensor.</p>\n </div>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":"47 19","pages":""},"PeriodicalIF":2.8000,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of separation science","FirstCategoryId":"5","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/jssc.202400441","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Molecularly imprinted polymers (MIPs) are very suitable for extraction, drug delivery systems, and sensors due to their good selective adsorption ability, but the difficulty of eluting templates during synthesis and the limitation of application scenarios put higher demands on MIPs. Stimuli-responsive MIPs (SR-MIPs) can actively respond to changes in external conditions to realize various functions, which provides new ideas for the further development of MIPs. This paper reviews the multiple response modes of MIPs, including the common temperature, pH, photo, magnetic, redox-responsive and rare gas, biomolecule, ion, and solvent-responsive MIPs, and explains the mechanism, composition, and applications of such SR-MIPs. These SR-MIPs and the resulting dual/multiple-responsive MIPs have good selectivity, and controllability, and are very promising for isolation and extraction, targeted drug delivery, and electro-sensor.
期刊介绍：
The Journal of Separation Science (JSS) is the most comprehensive source in separation science, since it covers all areas of chromatographic and electrophoretic separation methods in theory and practice, both in the analytical and in the preparative mode, solid phase extraction, sample preparation, and related techniques. Manuscripts on methodological or instrumental developments, including detection aspects, in particular mass spectrometry, as well as on innovative applications will also be published. Manuscripts on hyphenation, automation, and miniaturization are particularly welcome. Pre- and post-separation facets of a total analysis may be covered as well as the underlying logic of the development or application of a method.
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