Chemical enhancements and advanced manufacturing methods of Poly(Lactic acid) for tissue engineering applications

IF 4.1 2区化学 Q2 POLYMER SCIENCE

Polymer Pub Date : 2024-10-09 DOI:10.1016/j.polymer.2024.127691

Cole Martin Fredericks , Joshua K.I. Kunihiro , Hanjia Zheng , Naweed Rizwan Waghu , Milad Kamkar

引用次数: 0

Abstract

Poly(lactic acid) (PLA) is a highly versatile biobased polymer with significant promise as a 3D-printable material for tissue engineering applications. PLA is sustainably produced at low cost, and exhibits properties such as biodegradability, biocompatibility, appreciable mechanical properties, and its potential for modification by a multitude of different additives and processing methods. This work provides an overview of recent research on the advanced manufacturing of PLA for tissue engineering applications. It also covers the most widely used additives and surface modifications to PLA, the effects of different processing methods, and the current shortcomings and future directions in this field.

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用于组织工程应用的聚乳酸化学改良剂和先进制造方法

聚乳酸（PLA）是一种用途广泛的生物基聚合物，有望成为组织工程应用领域的三维打印材料。聚乳酸可持续生产，成本低廉，具有生物可降解性、生物相容性、可观的机械性能等特性，并可通过多种不同的添加剂和加工方法进行改性。本研究综述了近期有关组织工程应用聚乳酸先进制造技术的研究。它还涵盖了最广泛使用的添加剂和聚乳酸表面改性、不同加工方法的影响以及该领域目前存在的不足和未来的发展方向。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Polymer 化学-高分子科学

CiteScore

7.90

自引率

8.70%

发文量

959

审稿时长

32 days

期刊介绍： Polymer is an interdisciplinary journal dedicated to publishing innovative and significant advances in Polymer Physics, Chemistry and Technology. We welcome submissions on polymer hybrids, nanocomposites, characterisation and self-assembly. Polymer also publishes work on the technological application of polymers in energy and optoelectronics. The main scope is covered but not limited to the following core areas: Polymer Materials Nanocomposites and hybrid nanomaterials Polymer blends, films, fibres, networks and porous materials Physical Characterization Characterisation, modelling and simulation* of molecular and materials properties in bulk, solution, and thin films Polymer Engineering Advanced multiscale processing methods Polymer Synthesis, Modification and Self-assembly Including designer polymer architectures, mechanisms and kinetics, and supramolecular polymerization Technological Applications Polymers for energy generation and storage Polymer membranes for separation technology Polymers for opto- and microelectronics.