Cooccurrence of Capsular Liver Lesions Along with Peritoneal Carcinomatosis and Hematogenous Metastases in Ovarian Cancer Patients on Consecutive ¹⁸F-FDG PET/CT Studies.

IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Molecular Imaging and Radionuclide Therapy Pub Date : 2024-10-07 DOI:10.4274/mirt.galenos.2024.39269

Kemal Ünal, Levent Güner, Erkan Vardareli

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Abstract

Objectives: The aim of our study was to evaluate the cooccurrence of capsular liver lesions along with peritoneal carcinomatosis and hematogenous metastases in other regions of the body in ovarian cancer patients on follow-up F-18 fluorodeoxyglucose (¹⁸F-FDG) positron emission tomography/computed tomography (PET/CT) studies.

Methods: Consecutive ¹⁸F-FDG PET/CT studies of 54 women with ovarian cancer between August 2012 and January 2020 and a total of 192 scans were analysed retrospectively. All patients had at least one hepatic and/or capsular lesion with high ¹⁸F-FDG uptake and at least two PET/CT examinations.

Results: According to interpretation, of 54 patients with hepatic or capsular lesions, 44 (81.4%), 5 (9.3%) and 5 (9.3%) of them were concluded as perihepatic implants, hematogenous liver metastases and both, respectively. Accompanying peritoneal carcinomatosis on follow-up PET/CT images was found in 42 (95.4%) and 3 (60%) patients with solely capsular lesions and solely hematogenous liver metastases, respectively. Extrahepatic hematogenous organ metastases on follow-up PET/CT images were seen in 4 (9.0%) and 3 (60%) patients with solely capsular lesions and solely hematogenous liver metastases, respectively. Lungs, bones, spleen and brain were detected metastases sites.

Conclusion: Cooccurrence of peritoneal carcinomatosis in other regions of abdomen was found to be higher in comparison to hematogenous organ metastases on consecutive PET/CT studies of ovarian cancer patients with capsular liver lesions. The primary opinion of the nuclear medicine physician is essential along with the other patient data for differential diagnosis and treatment approach in this particular patient group.

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在连续的 18F-FDG PET/CT 研究中发现卵巢癌患者的囊性肝炎病变与腹膜癌肿和血行转移瘤同时存在。

研究目的我们的研究旨在评估随访 F-18 氟脱氧葡萄糖（18F-FDG）正电子发射断层扫描/计算机断层扫描（PET/CT）研究中卵巢癌患者肝囊病变与腹膜癌肿和身体其他区域血行转移的共存情况：回顾性分析了 2012 年 8 月至 2020 年 1 月期间对 54 名卵巢癌女性患者进行的连续 18F-FDG PET/CT 研究，共计 192 次扫描。所有患者都至少有一个肝脏和/或囊肿病灶具有高18F-FDG摄取，且至少接受过两次PET/CT检查：根据判读结果，在54例有肝脏或囊性病变的患者中，分别有44例（81.4%）、5例（9.3%）和5例（9.3%）被认定为肝周种植、血源性肝转移或两者兼而有之。42例（95.4%）和3例（60%）单纯囊性病变和单纯血源性肝转移的患者在随访PET/CT图像中发现伴有腹膜癌肿。在 PET/CT 随访图像上发现肝外血源性器官转移的患者分别有 4 例（9.0%）和 3 例（60%），分别为单纯囊性病变和单纯血源性肝转移。肺部、骨骼、脾脏和脑部也是检测到的转移部位：结论：在对有肝囊性病变的卵巢癌患者进行的连续 PET/CT 研究中发现，腹腔其他区域腹膜癌转移的并发率高于血源性器官转移。对于这一特殊患者群体，核医学医生的主要意见以及其他患者数据对于鉴别诊断和治疗方法至关重要。

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来源期刊

Molecular Imaging and Radionuclide Therapy RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

1.30

自引率

0.00%

发文量

期刊介绍： Molecular Imaging and Radionuclide Therapy (Mol Imaging Radionucl Ther, MIRT) is publishes original research articles, invited reviews, editorials, short communications, letters, consensus statements, guidelines and case reports with a literature review on the topic, in the field of molecular imaging, multimodality imaging, nuclear medicine, radionuclide therapy, radiopharmacy, medical physics, dosimetry and radiobiology.