Understanding the intricate impacts and mechanism of actions of adaptogens on reproductive function.

IF 1.8 4区生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY

Cell Biochemistry and Biophysics Pub Date : 2024-10-06 DOI:10.1007/s12013-024-01565-6

Precious Adeoye Oyedokun, Victory Jesutoyosi Ashonibare, Fidelis Batale Fabrael, Tunmise Maryanne Akhigbe, Marvelous Dasola Akangbe, Roland Eghoghosoa Akhigbe

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引用次数: 0

Abstract

Adaptogens, comprising plants and mushrooms, modulate the immune system, energy balance, and various physiological processes, including reproduction. Despite their potential benefits, the impact of adaptogens on reproductive function remains understudied. This review examines the effects of common adaptogens on male and female reproductive functions, highlighting their regulation of neuro-endocrine-immune interactions crucial for reproduction. While existing literature reveals varying impacts on reproductive function, most adaptogens exhibit beneficial effects, modulating neuroimmunology and promoting gonadal steroidogenesis, spermatogenesis, and folliculogenesis through direct mechanisms or suppression of oxidative stress and inflammation. Further experimental research is necessary to elucidate the mechanisms of action of adaptogens, which would significantly advance the management of reproductive disorders and other diseases. Validating these findings in clinical trials is also essential.

查看原文本刊更多论文

了解适应原对生殖功能的复杂影响和作用机制。

由植物和蘑菇组成的适应原能调节免疫系统、能量平衡和包括生殖在内的各种生理过程。尽管适应素具有潜在的益处，但其对生殖功能的影响仍未得到充分研究。这篇综述探讨了常见适应原对男性和女性生殖功能的影响，强调了它们对生殖过程中至关重要的神经-内分泌-免疫相互作用的调节作用。虽然现有文献显示适应原对生殖功能的影响各不相同，但大多数适应原都表现出有益的作用，通过直接机制或抑制氧化应激和炎症，调节神经免疫学，促进性腺类固醇生成、精子生成和卵泡生成。有必要开展进一步的实验研究，以阐明适应原的作用机制，这将极大地促进对生殖障碍和其他疾病的治疗。在临床试验中验证这些发现也是至关重要的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cell Biochemistry and Biophysics 生物-生化与分子生物学

CiteScore

4.40

自引率

0.00%

发文量

审稿时长

7.5 months

期刊介绍： Cell Biochemistry and Biophysics (CBB) aims to publish papers on the nature of the biochemical and biophysical mechanisms underlying the structure, control and function of cellular systems The reports should be within the framework of modern biochemistry and chemistry, biophysics and cell physiology, physics and engineering, molecular and structural biology. The relationship between molecular structure and function under investigation is emphasized. Examples of subject areas that CBB publishes are: · biochemical and biophysical aspects of cell structure and function; · interactions of cells and their molecular/macromolecular constituents; · innovative developments in genetic and biomolecular engineering; · computer-based analysis of tissues, cells, cell networks, organelles, and molecular/macromolecular assemblies; · photometric, spectroscopic, microscopic, mechanical, and electrical methodologies/techniques in analytical cytology, cytometry and innovative instrument design For articles that focus on computational aspects, authors should be clear about which docking and molecular dynamics algorithms or software packages are being used as well as details on the system parameterization, simulations conditions etc. In addition, docking calculations (virtual screening, QSAR, etc.) should be validated either by experimental studies or one or more reliable theoretical cross-validation methods.