Clinical Efficacy and Safety of Low-Energy Extracorporeal Shock Wave Therapy for Various Conditions of Deep Dermal and Subdermal Fibrosis.

IF 2 4区 医学 Q3 DERMATOLOGY
Jeongah Ko, Sung Bin Cho
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引用次数: 0

Abstract

Background: Extracorporeal shock wave therapy (ESWT) enhances extracellular matrix remodeling and tissue regeneration by promoting growth factor release, regulating blood and lymphatic flows, and reducing fat and fibrotic tissues. Focused shock wave therapy (F-SWT), radial shock wave therapy (R-SWT), and combined F-SWT and R-SWT have been used to deliver different patterns of shock energy depending on the characteristics of the target lesions.

Methods: We investigated the efficacy and safety of ESWT in patients with dermal and subdermal fibrosis. Fifty-two patients treated with F-SWT and/or R-SWT for dermal and subdermal fibrosis caused due to various reasons were retrospectively analyzed by reviewing their medical records, clinical images, and ultrasound study images.

Results: The mean number of pulses administered for F-SWT on the cheek, temple, and chin were 2600.0 ± 1040.8 shocks/session and for R-SWT were 5080.0 ± 2234.6 pulses/session, and the number of treatment sessions were 8.0 ± 4.4. In patients who were treated with ESWT on the abdomen, the mean number of pulses for F-SWT were 2600.0 ± 2408.3 shocks/session and for R-SWT were 8400.0 ± 894.4 pulses/session, and the number of treatment sessions were 3.2 ± 1.6. Most patients were satisfied with the results. Pain during ESWT was well tolerated and post-ESWT edema was more common in R-SWT than in F-SWT.

Conclusion: Our data demonstrated that ESWT effectively and safely improved the clinical appearance and functional movement of patients with dermal and subdermal fibrosis caused due to various reasons.

低能量体外冲击波疗法治疗各种真皮深层和皮下纤维化病症的临床疗效和安全性。
背景:体外冲击波疗法(ESWT)通过促进生长因子释放、调节血液和淋巴流动以及减少脂肪和纤维组织,增强细胞外基质重塑和组织再生。聚焦冲击波疗法(F-SWT)、径向冲击波疗法(R-SWT)以及 F-SWT 和 R-SWT 联合疗法可根据目标病变的特点提供不同的冲击能量模式:我们研究了 ESWT 对真皮和皮下纤维化患者的疗效和安全性。通过回顾病历、临床图像和超声研究图像,我们对52例因各种原因导致真皮和皮下纤维化而接受F-SWT和/或R-SWT治疗的患者进行了回顾性分析:在脸颊、太阳穴和下巴进行 F-SWT 治疗的平均脉冲数为 2600.0 ± 1040.8 次/次,R-SWT 治疗的平均脉冲数为 5080.0 ± 2234.6 次/次,治疗次数为 8.0 ± 4.4 次。在腹部接受 ESWT 治疗的患者中,F-SWT 的平均脉冲数为(2600.0 ± 2408.3)次/次,R-SWT 的平均脉冲数为(8400.0 ± 894.4)次/次,治疗次数为(3.2 ± 1.6)次。大多数患者对治疗效果表示满意。ESWT期间的疼痛耐受性良好,ESWT后水肿在R-SWT中比在F-SWT中更常见:我们的数据表明,ESWT 能有效、安全地改善各种原因导致的真皮和皮下纤维化患者的临床外观和功能活动。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Skin Research and Technology
Skin Research and Technology 医学-皮肤病学
CiteScore
3.30
自引率
9.10%
发文量
95
审稿时长
6-12 weeks
期刊介绍: Skin Research and Technology is a clinically-oriented journal on biophysical methods and imaging techniques and how they are used in dermatology, cosmetology and plastic surgery for noninvasive quantification of skin structure and functions. Papers are invited on the development and validation of methods and their application in the characterization of diseased, abnormal and normal skin. Topics include blood flow, colorimetry, thermography, evaporimetry, epidermal humidity, desquamation, profilometry, skin mechanics, epiluminiscence microscopy, high-frequency ultrasonography, confocal microscopy, digital imaging, image analysis and computerized evaluation and magnetic resonance. Noninvasive biochemical methods (such as lipids, keratin and tissue water) and the instrumental evaluation of cytological and histological samples are also covered. The journal has a wide scope and aims to link scientists, clinical researchers and technicians through original articles, communications, editorials and commentaries, letters, reviews, announcements and news. Contributions should be clear, experimentally sound and novel.
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