Outcomes after endovascular revascularization for chronic limb-threatening ischemia from the only Vascular Quality Initiative (VQI) center in Asia.

IF 3.9 2区 医学 Q1 PERIPHERAL VASCULAR DISEASE
Joel Jia Yi Soon, Ankur Patel, Hsien Ts'ung Luke Tay, Seck Guan Tan, Sivanathan Chandramohan, Charyl Jia Qi Yap, Stephanie Hui Min Chen, Kiang Hiong Tay, Tze Tec Chong
{"title":"Outcomes after endovascular revascularization for chronic limb-threatening ischemia from the only Vascular Quality Initiative (VQI) center in Asia.","authors":"Joel Jia Yi Soon, Ankur Patel, Hsien Ts'ung Luke Tay, Seck Guan Tan, Sivanathan Chandramohan, Charyl Jia Qi Yap, Stephanie Hui Min Chen, Kiang Hiong Tay, Tze Tec Chong","doi":"10.1016/j.jvs.2024.09.034","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>This study compares chronic limb-threatening ischemia disease characteristics and endovascular revascularization outcomes in a multi-ethnic Asian cohort vs their North American counterparts.</p><p><strong>Methods: </strong>The Society for Vascular Surgery Vascular Quality Initiative (VQI) registry database from the first and currently the only VQI center in Asia was reviewed to identify patients with chronic limb-threatening ischemia who underwent endovascular revascularization between July 2019 and April 2024. Standardized VQI reporting variables were compared against benchmarks derived from all participating centers in North America.</p><p><strong>Results: </strong>A total of 2862 endovascular revascularization procedures from our center were benchmarked against 129,347 procedures from 406 North American centers. Our cohort had a higher burden of comorbidities (diabetes mellitus, end-stage renal disease, cardiac disease) and presented with more advanced Wound, Ischemia, and foot Infection stages. Our patients had more heavily calcified and longer (14.8 cm vs 6.0 cm) diseased vessels with higher prevalence of multi-level (87% vs 54.6%), infrapopliteal (52.6% vs 38.9%), and inframalleolar (9.6% vs 2.4%) disease. Rates of technical success (92.7% vs 93%) and symptom improvement (39.1% vs 40.4%) were comparable between cohorts. However, 1-year mortality rates (28.9% vs 25.1%) and major amputation rates (13.3% vs 7.8%) were significantly higher.</p><p><strong>Conclusions: </strong>Short-term outcomes of technical success and symptom relief in our center were comparable to benchmarked North American outcomes despite having a cohort with more diseased vessels, higher Wound, Ischemia, and foot Infection stages, and more comorbidities. However, this cohort fared worse in longer term outcomes of 1-year mortality and major amputation rates. Further studies are required to elucidate the causes to improve these outcomes.</p>","PeriodicalId":17475,"journal":{"name":"Journal of Vascular Surgery","volume":" ","pages":""},"PeriodicalIF":3.9000,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Vascular Surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.jvs.2024.09.034","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PERIPHERAL VASCULAR DISEASE","Score":null,"Total":0}
引用次数: 0

Abstract

Objective: This study compares chronic limb-threatening ischemia disease characteristics and endovascular revascularization outcomes in a multi-ethnic Asian cohort vs their North American counterparts.

Methods: The Society for Vascular Surgery Vascular Quality Initiative (VQI) registry database from the first and currently the only VQI center in Asia was reviewed to identify patients with chronic limb-threatening ischemia who underwent endovascular revascularization between July 2019 and April 2024. Standardized VQI reporting variables were compared against benchmarks derived from all participating centers in North America.

Results: A total of 2862 endovascular revascularization procedures from our center were benchmarked against 129,347 procedures from 406 North American centers. Our cohort had a higher burden of comorbidities (diabetes mellitus, end-stage renal disease, cardiac disease) and presented with more advanced Wound, Ischemia, and foot Infection stages. Our patients had more heavily calcified and longer (14.8 cm vs 6.0 cm) diseased vessels with higher prevalence of multi-level (87% vs 54.6%), infrapopliteal (52.6% vs 38.9%), and inframalleolar (9.6% vs 2.4%) disease. Rates of technical success (92.7% vs 93%) and symptom improvement (39.1% vs 40.4%) were comparable between cohorts. However, 1-year mortality rates (28.9% vs 25.1%) and major amputation rates (13.3% vs 7.8%) were significantly higher.

Conclusions: Short-term outcomes of technical success and symptom relief in our center were comparable to benchmarked North American outcomes despite having a cohort with more diseased vessels, higher Wound, Ischemia, and foot Infection stages, and more comorbidities. However, this cohort fared worse in longer term outcomes of 1-year mortality and major amputation rates. Further studies are required to elucidate the causes to improve these outcomes.

亚洲唯一一家血管质量倡议(VQI)中心对慢性肢体缺血进行血管内再通术后的疗效。
简介:本研究比较了多种族亚洲队列与北美队列的慢性肢体危重性缺血(CLTI)疾病特征和血管内再植结果:这项研究比较了多种族亚洲队列与北美队列的慢性肢体缺血(CLTI)疾病特征和血管内再通治疗效果:我们对亚洲首个也是目前唯一一个VQI中心的血管外科学会血管质量倡议(SVS VQI)登记数据库进行了审查,以确定在2019年7月至2024年4月期间接受血管内血运重建的CLTI患者。将标准化的VQI报告变量与来自北美所有参与中心的基准进行了比较。结果:将来自我们中心的2862例血管内血运重建手术与来自北美406个中心的129347例血管内血运重建手术进行了比较。我们的患者合并症(糖尿病、终末期肾病、心脏病)较多,伤口、缺血和足部感染(WIfI)分期较晚。我们的患者钙化程度更高,病变血管更长(14.8 厘米对 6.0 厘米),多层次(87% 对 54.6%)、膝下(52.6% 对 38.9%)和踝下(9.6% 对 2.4%)病变的发生率更高。两组患者的技术成功率(92.7% 对 93%)和症状改善率(39.1% 对 40.4%)相当。然而,1年死亡率(28.9% vs 25.1%)和大截肢率(13.3% vs 7.8%)却明显更高:结论:尽管我们中心的队列中有更多的病变血管、更高的WIfI分期和合并症,但其技术成功率和症状缓解率的短期结果与北美的基准结果相当。然而,该组患者在1年死亡率和主要截肢率等长期结果方面表现较差。需要进一步的研究来阐明改善这些结果的原因。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
7.70
自引率
18.60%
发文量
1469
审稿时长
54 days
期刊介绍: Journal of Vascular Surgery ® aims to be the premier international journal of medical, endovascular and surgical care of vascular diseases. It is dedicated to the science and art of vascular surgery and aims to improve the management of patients with vascular diseases by publishing relevant papers that report important medical advances, test new hypotheses, and address current controversies. To acheive this goal, the Journal will publish original clinical and laboratory studies, and reports and papers that comment on the social, economic, ethical, legal, and political factors, which relate to these aims. As the official publication of The Society for Vascular Surgery, the Journal will publish, after peer review, selected papers presented at the annual meeting of this organization and affiliated vascular societies, as well as original articles from members and non-members.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信