Age- and gender-dependent impact of titanium vertebral augmentation implants combined with cementing on subsequent vertebral fracture incidence: A comparative study with cementing alone.

IF 2.6 3区医学 Q2 CLINICAL NEUROLOGY

European Spine Journal Pub Date : 2024-10-04 DOI:10.1007/s00586-024-08504-2

Chien-Ting Sun, Yi-Shan Yang, Chen-Ling Lan, Huy Minh Tran, Tuan Anh Pham, Yung-Hsiao Chiang, Chien-Min Lin, Yu-Kai Su, Yi-Chen Hsieh, Jiann-Her Lin

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引用次数: 0

Abstract

Purpose: To compare vertebroplasty (VP) and kyphoplasty (KP) with a titanium implantable vertebral augmentation device (TIVAD) in symptomatic subsequent vertebral compression fracture (SVCF) incidence among osteoporotic vertebral compression fracture (OVCF) patients stratified by age and sex.

Methods: This retrospective cohort study involved OVCF patients aged ≥ 50, who underwent KP with TIVAD or VP in our hospital from 2014 to 2019. Subgroup analysis was conducted to evaluate the efficacy of KP with TIVAD and VP in patients stratified by age and sex.

Results: The study included 472 patients (VP group: 303; TIVAD group: 169). SVCF incidence rates were 15.2% for VP group and 14.8% for TIVAD group (P = 0.87). In subgroup analysis, TIVAD group showed significantly lower SVCF incidence than VP group in women aged 50-70 (2.1% vs 14.3%; P = 0.03) and had significantly higher SVCF incidence than VP group in women aged > 70 (24.2% vs 13.1%; P = 0.02). In men, adjacent SVCF incidence was significantly lower in TIVAD group than VP group (0% vs 14.1%; P = 0.03).

Conclusion: Compared to VP, TIVAD is associated with lower symptomatic SVCF rate in men and younger women aged 50-70 but not in older women aged > 70. Age and gender may influence SVCF incidence.

Level of evidence: Diagnostic: individual cross-sectional studies with consistently applied reference standard and blinding.

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与年龄和性别相关的钛椎体增强植入物结合骨水泥对后续椎体骨折发生率的影响：与单纯骨水泥植入的比较研究。

目的：比较椎体成形术（VP）和带钛植入式椎体增强装置（TIVAD）的椎体成形术（KP）在按年龄和性别分层的骨质疏松性椎体压缩骨折（OVCF）患者中无症状继发性椎体压缩骨折（SVCF）发生率：这项回顾性队列研究涉及2014年至2019年在我院接受KP与TIVAD或VP的年龄≥50岁的OVCF患者。研究进行了亚组分析，以评估KP联合TIVAD和VP对不同年龄和性别患者的疗效：研究共纳入 472 例患者（VP 组：303 例；TIVAD 组：169 例）。VP 组 SVCF 发生率为 15.2%，TIVAD 组为 14.8%（P = 0.87）。在亚组分析中，TIVAD组在50-70岁女性中的SVCF发生率明显低于VP组（2.1% vs 14.3%; P = 0.03），而在70岁以上女性中，TIVAD组的SVCF发生率明显高于VP组（24.2% vs 13.1%; P = 0.02）。在男性中，TIVAD组的邻近SVCF发生率明显低于VP组（0% vs 14.1%；P = 0.03）：结论：与 VP 相比，TIVAD 在男性和 50-70 岁的年轻女性中与较低的无症状 SVCF 发生率相关，但在年龄大于 70 岁的老年女性中则与较低的无症状 SVCF 发生率无关。年龄和性别可能会影响SVCF的发生率：诊断性：具有一致参考标准和盲法的单项横断面研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Spine Journal 医学-临床神经学

CiteScore

4.80

自引率

10.70%

发文量

373

审稿时长

2-4 weeks

期刊介绍： "European Spine Journal" is a publication founded in response to the increasing trend toward specialization in spinal surgery and spinal pathology in general. The Journal is devoted to all spine related disciplines, including functional and surgical anatomy of the spine, biomechanics and pathophysiology, diagnostic procedures, and neurology, surgery and outcomes. The aim of "European Spine Journal" is to support the further development of highly innovative spine treatments including but not restricted to surgery and to provide an integrated and balanced view of diagnostic, research and treatment procedures as well as outcomes that will enhance effective collaboration among specialists worldwide. The “European Spine Journal” also participates in education by means of videos, interactive meetings and the endorsement of educative efforts. Official publication of EUROSPINE, The Spine Society of Europe