Pannus formation: a rare culprit of early bioprosthetic valve dysfunction-a case report.

Pub Date : 2024-10-03 eCollection Date: 2024-10-01 DOI:10.1093/ehjcr/ytae518

Sho Takemoto, Hiroshi Kumano, Junichi Shimamura, Akira Shiose

{"title":"Pannus formation: a rare culprit of early bioprosthetic valve dysfunction-a case report.","authors":"Sho Takemoto, Hiroshi Kumano, Junichi Shimamura, Akira Shiose","doi":"10.1093/ehjcr/ytae518","DOIUrl":null,"url":null,"abstract":"Background: Early bioprosthetic valve dysfunction (BVD) due to pannus formation is uncommon in elderly patients, and only a limited number of cases have been reported.Case summary: An 84-year-old man presented with exertional dyspnoea 3 years after surgical aortic valve replacement (SAVR) with a 19 mm Epic™ valve (Abbott, Santa Clara, CA, USA). Transthoracic echocardiography demonstrated progressive BVD, and cardiac computed tomography (CT) revealed sub-aortic pannus formation. Re-operative SAVR was performed using a 19 mm INSPIRIS RESILIA® valve (Edwards Lifesciences, Irvine, CA, USA), and pathological examination confirmed valve leaflet deformation caused by pannus overgrowth. At the 18-month follow-up, the patient exhibited favourable progress, with no indications of BVD or pannus recurrence.Discussion: This case highlights the importance of recognizing early pannus formation as a cause of BVD, even in elderly patients. Early detection of BVD based on clinical symptoms and echocardiography is vital to allow timely surgical intervention before the deterioration of cardiac function. Cardiac CT helps to differentiate pannus from thrombus formation and guide treatment decisions.","PeriodicalId":0,"journal":{"name":"","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11448332/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/ehjcr/ytae518","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/10/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Early bioprosthetic valve dysfunction (BVD) due to pannus formation is uncommon in elderly patients, and only a limited number of cases have been reported.

Case summary: An 84-year-old man presented with exertional dyspnoea 3 years after surgical aortic valve replacement (SAVR) with a 19 mm Epic™ valve (Abbott, Santa Clara, CA, USA). Transthoracic echocardiography demonstrated progressive BVD, and cardiac computed tomography (CT) revealed sub-aortic pannus formation. Re-operative SAVR was performed using a 19 mm INSPIRIS RESILIA® valve (Edwards Lifesciences, Irvine, CA, USA), and pathological examination confirmed valve leaflet deformation caused by pannus overgrowth. At the 18-month follow-up, the patient exhibited favourable progress, with no indications of BVD or pannus recurrence.

Discussion: This case highlights the importance of recognizing early pannus formation as a cause of BVD, even in elderly patients. Early detection of BVD based on clinical symptoms and echocardiography is vital to allow timely surgical intervention before the deterioration of cardiac function. Cardiac CT helps to differentiate pannus from thrombus formation and guide treatment decisions.

查看原文

结节形成：生物人工瓣膜早期功能障碍的罕见元凶--病例报告。

背景：病例摘要：一名 84 岁的男性在使用 19 毫米 Epic™ 瓣膜（雅培，美国加利福尼亚州圣克拉拉市）进行主动脉瓣置换手术 (SAVR) 3 年后出现劳力性呼吸困难。经胸超声心动图显示 BVD 进行性发展，心脏计算机断层扫描（CT）显示主动脉瓣下有脓肿形成。患者使用 19 毫米 INSPIRIS RESILIA® 瓣膜（Edwards Lifesciences，Irvine，CA，USA）再次进行了 SAVR 手术，病理检查证实瓣叶变形是由长脓过度生长引起的。在18个月的随访中，患者的病情进展良好，没有BVD或膜囊复发的迹象：讨论：本病例强调了认识到早期息肉形成是 BVD 病因的重要性，即使在老年患者中也是如此。根据临床症状和超声心动图早期发现 BVD 至关重要，可在心脏功能恶化前及时进行手术干预。心脏 CT 有助于区分心包积液和血栓形成，并指导治疗决策。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文