Co-metabolism of microorganisms: A study revealing the mechanism of antibiotic removal, progress of biodegradation transformation pathways.

IF 8.2 1区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Science of the Total Environment Pub Date : 2024-10-01 DOI:10.1016/j.scitotenv.2024.176561

Ke Zhao, Tingting Si, Shenghe Liu, Gaolei Liu, Donghao Li, Fengxiang Li

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Abstract

The widespread use of antibiotics has resulted in large quantities of antibiotic residues entering aquatic environments, which can lead to the development of antibiotic-resistant bacteria and antibiotic-resistant genes, posing a potential environmental risk and jeopardizing human health. Constructing a microbial co-metabolism system has become an effective measure to improve the removal efficiency of antibiotics by microorganisms. This paper reviews the four main mechanisms involved in microbial removal of antibiotics: bioaccumulation, biosorption, biodegradation and co-metabolism. The promotion of extracellular polymeric substances for biosorption and extracellular degradation and the regulation mechanism of enzymes in biodegradation by microorganisms processes are detailed therein. Transformation pathways for microbial removal of antibiotics are discussed. Bacteria, microalgae, and microbial consortia's roles in antibiotic removal are outlined. The factors influencing the removal of antibiotics by microbial co-metabolism are also discussed. Overall, this review summarizes the current understanding of microbial co-metabolism for antibiotic removal and outlines future research directions.

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微生物的共代谢：揭示抗生素去除机制和生物降解转化途径进展的研究。

抗生素的广泛使用导致大量抗生素残留物进入水生环境，从而可能导致抗生素耐药菌和抗生素耐药基因的产生，带来潜在的环境风险并危害人类健康。构建微生物共代谢系统已成为提高微生物去除抗生素效率的有效措施。本文综述了微生物去除抗生素的四种主要机制：生物蓄积、生物吸附、生物降解和共代谢。其中详细介绍了细胞外高分子物质对生物吸附和细胞外降解的促进作用，以及微生物生物降解过程中酶的调节机制。讨论了微生物去除抗生素的转化途径。概述了细菌、微藻和微生物联合体在去除抗生素中的作用。还讨论了影响微生物协同代谢去除抗生素的因素。总之，本综述总结了目前对微生物共代谢去除抗生素的理解，并概述了未来的研究方向。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Science of the Total Environment 环境科学-环境科学

CiteScore

17.60

自引率

10.20%

发文量

8726

审稿时长

2.4 months

期刊介绍： The Science of the Total Environment is an international journal dedicated to scientific research on the environment and its interaction with humanity. It covers a wide range of disciplines and seeks to publish innovative, hypothesis-driven, and impactful research that explores the entire environment, including the atmosphere, lithosphere, hydrosphere, biosphere, and anthroposphere. The journal's updated Aims & Scope emphasizes the importance of interdisciplinary environmental research with broad impact. Priority is given to studies that advance fundamental understanding and explore the interconnectedness of multiple environmental spheres. Field studies are preferred, while laboratory experiments must demonstrate significant methodological advancements or mechanistic insights with direct relevance to the environment.