Role of stereotactic radiotherapy in the management of small-cell lung cancer

IF 1.5 4区 医学 Q4 ONCOLOGY
François Lucia , Delphine Antoni , Loïg Vaugier , Loïg Duvergé , Sébastien Thureau , Vincent Bourbonne
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引用次数: 0

Abstract

Small-cell lung cancer is the most aggressive form of lung neoplasia, treated in recent decades with chemoradiotherapy in case of limited stage and chemotherapy alone at the metastatic stage. In the last few years, the advent of immunotherapy has changed the landscape in the treatment of non-small-cell lung cancer, and to a lesser degree in small-cell lung cancer. Despite the recent advances in research, small-cell lung cancer is still considered an aggressive and lethal disease characterized by high recurrence or metastatic potential. As stereotactic radiotherapy has established itself as the standard of care in the early stage of inoperable non-small-cell lung cancer and in metastatic disease to treat brain and extracranial metastases, these same issues now arise in the management of small-cell lung cancer. This article aims to review the current knowledge and the potential of stereotactic radiotherapy in small-cell lung cancer.
立体定向放射治疗在小细胞肺癌治疗中的作用。
小细胞肺癌是肺部肿瘤中最具侵袭性的一种,近几十年来,对局限期肺癌采用化学放疗,对转移期肺癌仅采用化疗。最近几年,免疫疗法的出现改变了非小细胞肺癌的治疗格局,也在一定程度上改变了小细胞肺癌的治疗格局。尽管最近的研究取得了进展,但小细胞肺癌仍被认为是一种具有侵袭性和致命性的疾病,其特点是复发率高或转移潜力大。由于立体定向放射治疗已成为无法手术的非小细胞肺癌早期治疗以及治疗脑转移和颅外转移疾病的标准疗法,这些问题现在也出现在小细胞肺癌的治疗中。本文旨在回顾立体定向放射治疗在小细胞肺癌中的现有知识和潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Cancer Radiotherapie
Cancer Radiotherapie 医学-核医学
CiteScore
2.20
自引率
23.10%
发文量
129
审稿时长
63 days
期刊介绍: Cancer/radiothérapie se veut d''abord et avant tout un organe francophone de publication des travaux de recherche en radiothérapie. La revue a pour objectif de diffuser les informations majeures sur les travaux de recherche en cancérologie et tout ce qui touche de près ou de loin au traitement du cancer par les radiations : technologie, radiophysique, radiobiologie et radiothérapie clinique.
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