Spontaneous bacterial peritonitis and soft tissue healing after tooth extraction in liver cirrhosis patients.

IF 2 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE
Gustavo Souza Galvão, Juliana Bertoldi Franco, Maria Paula Siqueira de Melo Peres, Gabriela Bănacu Melo, Jefferson R Tenório, Janaina B Medina, Camila de Barros Gallo, Karem L Ortega
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引用次数: 0

Abstract

Objective: The objective of this study was to identify the association between tooth extraction and occurrence of spontaneous bacterial peritonitis (SBP) and to assess delayed soft tissue healing of extraction sockets in patients with cirrhosis.

Study design: One hundred nineteen participants awaiting liver transplantation who required tooth extraction were included. Seven days before the surgery, the patients underwent panoramic radiography and laboratory examinations. Soft tissue healing was evaluated 7 days after the tooth extraction and medical records were checked after 21 days for development of SBP. The relationship between predictive factors and outcomes was assessed by using multiple binomial logistic regression.

Results: One hundred ninety-five teeth were extracted, resulting in 146 alveolar wounds, in which the majority (47%) consisted of alveolar sockets of multirooted teeth. One participant was diagnosed with SBP (Escherichia coli [E. coli]) and another diagnosed with bacterascites (Streptococcus viridans [S. viridans] group), occurring 11 and 6 days after tooth extraction. Poor soft tissue healing was observed in 20 (13.7%) patients, which was correlated to 2 risk factors, that is, jaundice (P = .007, adjusted odds ratio [OR] = 4.91, 95% confidence interval [CI] = 1.56-15.47) and moderate neutropenia (P = .048, adjusted OR = 13.99, 95% CI = 1.02-192.07).

Conclusions: No association was found between tooth extraction and SBP in patients with cirrhosis. The delayed soft tissue healing was related to jaundice (hyperbilirubinemia) and moderate neutropenia.

肝硬化患者拔牙后的自发性细菌性腹膜炎和软组织愈合。
研究目的本研究旨在确定肝硬化患者拔牙与自发性细菌性腹膜炎(SBP)发生之间的关联,并评估拔牙窝软组织延迟愈合的情况:研究设计:共纳入了 119 名需要拔牙的肝移植候诊者。手术前七天,患者接受全景放射摄影和实验室检查。拔牙后 7 天评估软组织愈合情况,21 天后检查病历以确定是否出现 SBP。采用多元二项式逻辑回归评估了预测因素与结果之间的关系:共拔除 195 颗牙齿,造成 146 处牙槽骨伤口,其中大部分(47%)为多根牙齿的牙槽骨伤口。一名受试者被诊断为 SBP(大肠杆菌),另一名受试者被诊断为菌斑(病毒性链球菌),分别发生在拔牙后 11 天和 6 天。20例(13.7%)患者的软组织愈合不良,这与两个风险因素有关,即黄疸(P = .007,调整后比值比 [OR] = 4.91,95% 置信区间 [CI] = 1.56-15.47)和中性粒细胞减少(P = .048,调整后比值比 [OR] = 13.99,95% 置信区间 [CI] = 1.02-192.07):结论:肝硬化患者拔牙与SBP之间没有关联。软组织愈合延迟与黄疸(高胆红素血症)和中性粒细胞减少症有关。
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来源期刊
Oral Surgery Oral Medicine Oral Pathology Oral Radiology
Oral Surgery Oral Medicine Oral Pathology Oral Radiology DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
3.80
自引率
6.90%
发文量
1217
审稿时长
2-4 weeks
期刊介绍: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology is required reading for anyone in the fields of oral surgery, oral medicine, oral pathology, oral radiology or advanced general practice dentistry. It is the only major dental journal that provides a practical and complete overview of the medical and surgical techniques of dental practice in four areas. Topics covered include such current issues as dental implants, treatment of HIV-infected patients, and evaluation and treatment of TMJ disorders. The official publication for nine societies, the Journal is recommended for initial purchase in the Brandon Hill study, Selected List of Books and Journals for the Small Medical Library.
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