Clinical response to nonsurgical periodontal therapy is associated with decreased serum leukocyte count and uric acid levels in kidney transplant recipients.

IF 2.2 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Applied Oral Science Pub Date : 2024-09-30 eCollection Date: 2024-01-01 DOI:10.1590/1678-7757-2024-0206

Samira Vasconcelos Gomes, Danila Lorena Nunes-Dos-Santos, Luciana Salles Branco-De-Almeida, Bruno Braga Benatti, Vandilson Rodrigues

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引用次数: 0

Abstract

Objective: This study sought to investigate the relationship between clinical response to nonsurgical periodontal therapy (NSPT) and serum changes in leukocyte count, fasting blood glucose, hemoglobin, hematocrit, creatinine, and uric acid in kidney transplant recipients (KTR).

Methodology: A prospective study was performed on 20 KTRs. Periodontal and serum data were collected before and 90 days after NSPT, and delta values (Δ = after NSPT - before) were calculated. Periodontal assessment included periodontal probing depth (PPD), clinical attachment level (CAL), and bleeding on probing (BOP). Patients were classified based on the presence of periodontitis and then categorized into stages.

Results: Patients showed a reduction in the percentage of sites with PPD≥3mm, PPD≥4 mm and BOP, after NSPT. There was a direct correlation between the deltas of leukocyte count and CAL ≥3 mm (r=0.645, P=0.002) and BOP (r=0.663, P=0.001), and the deltas of uric acid and CAL ≥3 mm (r=0.562, P=0.010).

Conclusion: A good clinical response to NSPT may affect the reduction of serum levels of leukocyte count and uric acid, suggesting a beneficial effect on systemic health in KTR.

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肾移植受者对非手术牙周治疗的临床反应与血清白细胞计数和尿酸水平下降有关。

研究目的本研究旨在探讨非手术牙周治疗（NSPT）的临床反应与肾移植受者（KTR）血清中白细胞计数、空腹血糖、血红蛋白、血细胞比容、肌酐和尿酸变化之间的关系：对 20 名肾移植受者进行了前瞻性研究。方法：对 20 名肾移植受者进行了前瞻性研究，收集了 NSPT 前和 NSPT 后 90 天的牙周和血清数据，并计算了 delta 值（Δ = NSPT 后 - NSPT 前）。牙周评估包括牙周探诊深度（PPD）、临床附着水平（CAL）和探诊出血量（BOP）。根据牙周炎的存在情况对患者进行分类，然后将其分为不同阶段：结果：患者在接受 NSPT 治疗后，PPD≥3 毫米、PPD≥4 毫米和 BOP 的部位比例均有所下降。白细胞计数与CAL≥3毫米（r=0.645，P=0.002）和BOP（r=0.663，P=0.001）的相关性，以及尿酸与CAL≥3毫米（r=0.562，P=0.010）的相关性：结论：对 NSPT 的良好临床反应可能会影响血清中白细胞计数和尿酸水平的降低，这表明对 KTR 的全身健康有益。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Applied Oral Science 医学-牙科与口腔外科

CiteScore

4.80

自引率

3.70%

发文量

审稿时长

4-8 weeks

期刊介绍： The Journal of Applied Oral Science is committed in publishing the scientific and technologic advances achieved by the dental community, according to the quality indicators and peer reviewed material, with the objective of assuring its acceptability at the local, regional, national and international levels. The primary goal of The Journal of Applied Oral Science is to publish the outcomes of original investigations as well as invited case reports and invited reviews in the field of Dentistry and related areas.