COVID-19 infection after vaccination.

Pub Date : 2024-08-30 eCollection Date: 2024-01-01 DOI:10.22088/cjim.15.4.644

Mana Baziboroun, Sayareh Hosseinzadeh, Hemmat Gholinia, Farzin Sadeghi, Yousef Yahyapour

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Abstract

Background: Although vaccination is the most effective and specific approach for prevention of infectious diseases, but in a small percentage of vaccinated person's breakthrough infections can occur. This study aimed to determine the effectiveness of different common coronavirus vaccines in this area.

Methods: 109 COVID-19 vaccinated patients were enrolled, with different types of vaccines (Sinopharm, AstraZeneca, Sputnic, Bharath, CovIran Barkat and Pasto-CoV) and time of administration in 2021 in Babol, Iran. Patients after 14 days of administration of the final dose of corona vaccines with positive COVID-19 RT-PCR test entered to study. Patients' data such as RT-PCR, type of vaccine, age, sex and outcome were collected using electronic medical records.

Results: 47 patients were not fully vaccinated, 62 had two vaccine doses and 51 were fully vaccinated and considered to a breakthrough infection. Although, most of the patients with SARS-CoV-2 infection were either mild (n=18 [16.56%]), or moderate (n=86 [78.9%]), 5 (4.6%) patients had severe or critical illness, of whom 3 admitted in intensive care unit, 3 intubated, and 4 died. The average age of the participants with COVID-19 infections was 61.23 ± 19.91 years.

Conclusion: Based on our results, the COVID-19 breakthrough occurring with two doses of current vaccines were mild and moderate.

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接种疫苗后感染 COVID-19。

背景：虽然接种疫苗是预防传染病最有效、最特异的方法，但少数接种者可能会发生突破性感染。本研究旨在确定不同的常见冠状病毒疫苗在这方面的有效性。方法：2021 年，在伊朗巴博勒，109 名接种过 COVID-19 疫苗的患者被纳入研究，他们接种了不同类型的疫苗（国药、阿斯利康、Sputnic、Bharath、CovIran Barkat 和 Pasto-CoV），接种时间也不同。接种最后一剂电晕疫苗 14 天后，COVID-19 RT-PCR 检测呈阳性的患者进入研究。研究使用电子病历收集患者的数据，如 RT-PCR、疫苗类型、年龄、性别和结果：结果：47 名患者未完全接种疫苗，62 名患者接种了两剂疫苗，51 名患者完全接种疫苗并被视为突破性感染。虽然大多数 SARS-CoV-2 感染者为轻度（18 人 [16.56%]）或中度（86 人 [78.9%]），但有 5 人（4.6%）病情严重或危重，其中 3 人住进重症监护室，3 人插管，4 人死亡。COVID-19感染者的平均年龄为（61.23 ± 19.91）岁：根据我们的研究结果，接种两剂现行疫苗后出现的 COVID-19 突破性感染为轻度和中度。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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