The Usefulness of Cardiopulmonary Exercise Testing to Detect Functional Improvement after Transcatheter Valve Procedures: What Do We Know So Far?

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-09-20 eCollection Date: 2024-09-01 DOI:10.31083/j.rcm2509336

Luca Cumitini, Ailia Giubertoni, Giuseppe Patti

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引用次数: 0

Abstract

Transcatheter valve procedures have become a cornerstone in the management of patients with valvular heart disease and high surgical risk, especially for aortic stenosis and mitral and tricuspid regurgitation. Cardiopulmonary exercise testing (CPET) is generally considered the gold standard for objectively quantifying functional capacity, providing a comprehensive evaluation of the human body's performance, particularly in patients with heart failure (HF). Its accurate assessment is valuable for exploring the pathogenetic mechanisms implicated in HF-related functional impairment. It is also useful for objectively staging the clinical severity and the prognosis of the disease. The improvement in functional capacity after transcatheter valve procedures may be clinically relevant and may provide prognostic information, even in this setting. However, it remains to be fully determined as data on the topic are limited. This review aims to summarize the available evidence on the usefulness of CPET to assess functional improvement in patients undergoing transcatheter valve procedures.

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心肺运动测试对检测经导管瓣膜术后功能改善的有用性：我们目前了解多少？

经导管瓣膜手术已成为治疗瓣膜性心脏病和高手术风险患者的基石，尤其是主动脉瓣狭窄、二尖瓣和三尖瓣反流患者。心肺运动测试（CPET）通常被认为是客观量化功能能力的黄金标准，可全面评估人体机能，尤其是心力衰竭（HF）患者的机能。它的准确评估对于探索心衰相关功能障碍的发病机制非常有价值。它还有助于对疾病的临床严重程度和预后进行客观分期。即使在这种情况下，经导管瓣膜手术后功能能力的改善也可能与临床相关，并可能提供预后信息。然而，由于相关数据有限，这一点仍有待全面确定。本综述旨在总结 CPET 在评估经导管瓣膜手术患者功能改善方面的实用性的现有证据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.