Superior Identification of Metastatic Lesions by 68 Ga-FAPI-46 PET/CT Than 18 F-FDG PET/CT in Hepatic Solitary Fibrous Tumor.

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2024-12-01 Epub Date: 2024-10-02 DOI:10.1097/RLU.0000000000005453

Kaili Fu, Liang Zhao, Jiayu Cai, Lingyu Yu, Haojun Chen

引用次数: 0

Abstract

Abstract: Solitary fibrous tumors (SFTs) are fibroblast tumors that occur mainly in the pleura. Hepatic SFT with skeleton metastases was rarely documented. In this case, we report the contrast-enhanced CT, 18 F-FDG, and 68 Ga-FAPI-46 PET/CT findings of a rare hepatic SFT with bone metastases. 68 Ga-FAPI-46 PET/CT showed much higher tumor-to-background contrast of hepatic tumors and revealed more metastatic bone lesions than 18 F-FDG PET/CT. This case demonstrated the superiority of 68 Ga-FAPI-46 PET/CT over 18 F-FDG for identifying metastatic lesions in malignant SFTs. This observation may add information on the benefit of FAPI PET/CT in SFT staging.

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在肝单发纤维瘤中，68Ga-FAPI-46 PET/CT 比 18F-FDG PET/CT 更好地识别转移病灶

摘要：孤立性纤维瘤（SFTs）是主要发生在胸膜的成纤维细胞肿瘤。肝脏 SFT 伴有骨骼转移的病例很少见。在本病例中，我们报告了一例罕见的肝脏SFT伴骨转移的对比增强CT、18F-FDG和68Ga-FAPI-46 PET/CT结果。与 18F-FDG PET/CT 相比，68Ga-FAPI-46 PET/CT 显示出更高的肝肿瘤与背景对比度，并显示出更多的骨转移病灶。该病例表明，68Ga-FAPI-46 PET/CT 在识别恶性 SFT 转移病灶方面优于 18F-FDG。这一观察结果可为FAPI PET/CT在SFT分期中的益处提供更多信息。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.