Recent advancements in nanozyme hydrogel based system for enhanced sensing applications

IF 10.61 Q3 Biochemistry, Genetics and Molecular Biology

Biosensors and Bioelectronics: X Pub Date : 2024-09-24 DOI:10.1016/j.biosx.2024.100548

Simran Makkar , Nikita Sarawagi , Nitesh Priyadarshi , Sunaina Kaul , Palakjot Kour Sodhi , Ajay Kumar Srivastava , Nitin Kumar Singhal

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Abstract

In recent years, combining hydrogels with nanozymes has shown promise as a platform for sensing applications. Nanozymes are simple, affordable, and stable alternatives that use enzyme-like capabilities. Conversely, hydrogels provide hydrated, biocompatible environments, which enhance the stability and activity of nanozymes. The most recent advancements in nanozyme-hydrogel hybrid sensing systems are examined in this study, with a focus on their enzymatic activities—peroxidase and oxidase mimetics—and how they can be used to detect a variety of analytes, such as glucose, pesticide, and many more.

In addition to simulating the biological environment, the synergistic combination of hydrogels and nanozyme improves the biosensor's sensitivity, specificity, and fast reaction times. These hybrid systems also provide an extensible framework for integrating multiple sensory modalities into a single functional device. This review highlights the groundbreaking potential and uses of hydrogel sensors based on nanozymes in environmental and medical diagnostics and potential future developments.

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基于纳米酶的水凝胶系统在增强传感应用方面的最新进展

近年来，水凝胶与纳米酶的结合已显示出作为传感应用平台的前景。纳米酶是一种简单、经济、稳定的替代品，具有类似酶的功能。相反，水凝胶提供了水合的、生物兼容的环境，从而提高了纳米酶的稳定性和活性。本研究探讨了纳米酶-水凝胶混合传感系统的最新进展，重点是它们的酶活性--过氧化物酶和氧化酶模拟物--以及它们如何用于检测葡萄糖、农药等多种分析物。这些混合系统还提供了一个可扩展的框架，可将多种感官模式集成到单一功能装置中。本综述重点介绍了基于纳米酶的水凝胶传感器在环境和医疗诊断中的突破性潜力和用途，以及未来的潜在发展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biosensors and Bioelectronics: X Biochemistry, Genetics and Molecular Biology-Biophysics

CiteScore

4.60

自引率

0.00%

发文量

166

审稿时长

54 days

期刊介绍： Biosensors and Bioelectronics: X, an open-access companion journal of Biosensors and Bioelectronics, boasts a 2020 Impact Factor of 10.61 (Journal Citation Reports, Clarivate Analytics 2021). Offering authors the opportunity to share their innovative work freely and globally, Biosensors and Bioelectronics: X aims to be a timely and permanent source of information. The journal publishes original research papers, review articles, communications, editorial highlights, perspectives, opinions, and commentaries at the intersection of technological advancements and high-impact applications. Manuscripts submitted to Biosensors and Bioelectronics: X are assessed based on originality and innovation in technology development or applications, aligning with the journal's goal to cater to a broad audience interested in this dynamic field.