Inflammatory myopathies in 2024: Better classify them to better treat them

IF 2.8 4区医学 Q2 CLINICAL NEUROLOGY

Revue neurologique Pub Date : 2024-11-01 DOI:10.1016/j.neurol.2024.09.003

引用次数: 0

Abstract

The discovery, over the last forty years or so, of specific myositis auto-antibodies (easily dosed in routine nowadays) and the fine clinically and pathologically phenotypic descriptions of affected patients have made it possible to review the classification of inflammatory myopathies. The arrival of “omic” techniques has also led to the discovery of different pathophysiological mechanisms among these different subgroups of myositis. Naturally, therapeutic approaches specifically targeting the representative abnormal pathways of each subgroup are being evaluated. This modern approach to myositis, which is clinical, pathophysiological, and therapeutic in the making, is presented in this review article.

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2024 年的炎症性肌病：更好地分类，更好地治疗。

在过去的四十多年里，特异性肌炎自身抗体的发现（如今很容易在常规治疗中使用）以及对受影响患者的临床和病理表型的详细描述，使我们有可能重新审视炎症性肌病的分类。此外，"奥米克 "技术的出现也发现了肌炎不同亚群的不同病理生理机制。自然而然，针对每个亚组的代表性异常通路的治疗方法也在评估之中。这篇综述文章介绍了这种治疗肌炎的现代方法，它集临床、病理生理学和治疗学于一体。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Revue neurologique 医学-临床神经学

CiteScore

4.80

自引率

0.00%

发文量

598

审稿时长

55 days

期刊介绍： The first issue of the Revue Neurologique, featuring an original article by Jean-Martin Charcot, was published on February 28th, 1893. Six years later, the French Society of Neurology (SFN) adopted this journal as its official publication in the year of its foundation, 1899. The Revue Neurologique was published throughout the 20th century without interruption and is indexed in all international databases (including Current Contents, Pubmed, Scopus). Ten annual issues provide original peer-reviewed clinical and research articles, and review articles giving up-to-date insights in all areas of neurology. The Revue Neurologique also publishes guidelines and recommendations. The Revue Neurologique publishes original articles, brief reports, general reviews, editorials, and letters to the editor as well as correspondence concerning articles previously published in the journal in the correspondence column.