Outpatient Laboratory Monitoring for Antibiotic-related Adverse Events in Children With Acute Hematogenous Osteomyelitis.

IF 2.9 4区医学 Q3 IMMUNOLOGY

Pediatric Infectious Disease Journal Pub Date : 2024-09-30 DOI:10.1097/INF.0000000000004576

Felicia O Rosiji, Marritta Joseph, Lauren M Sommer, Sheldon L Kaplan, Jesus G Vallejo, J Chase McNeil

引用次数: 0

Abstract

Monitoring for antibiotic-related lab abnormalities (ARLA), including hematologic, renal, and/or hepatic toxicity, in pediatric osteomyelitis is common. In 240 cases of osteomyelitis with outpatient laboratory monitoring, ARLA occurred in 13.3% with the most common finding being neutropenia. ARLA impacted antibiotic therapy in <1% of subjects, however, raising questions about the value of such monitoring being performed routinely.

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急性血源性骨髓炎患儿抗生素相关不良事件的门诊实验室监测。

监测抗生素相关实验室异常（ARLA），包括血液学、肾脏和/或肝脏毒性，在小儿骨髓炎中很常见。在 240 例接受门诊实验室监测的骨髓炎病例中，有 13.3% 出现了 ARLA，最常见的结果是中性粒细胞减少。ARLA影响抗生素治疗的病例

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pediatric Infectious Disease Journal 医学-传染病学

CiteScore

6.30

自引率

2.80%

发文量

566

审稿时长

2-4 weeks

期刊介绍： The Pediatric Infectious Disease Journal® (PIDJ) is a complete, up-to-the-minute resource on infectious diseases in children. Through a mix of original studies, informative review articles, and unique case reports, PIDJ delivers the latest insights on combating disease in children — from state-of-the-art diagnostic techniques to the most effective drug therapies and other treatment protocols. It is a resource that can improve patient care and stimulate your personal research.