Cytokine Profile in Children Following SARS-CoV-2 Infection: Preliminary Findings.

IF 2.9 4区医学 Q3 IMMUNOLOGY

Pediatric Infectious Disease Journal Pub Date : 2024-10-01 DOI:10.1097/INF.0000000000004558

Danilo Buonsenso, Anna Camporesi, Gabriele Di Sante, Michela Sali, Maria Del Carmen Pereyra Boza, Rosa Morello, Piero Valentini, Francesca Raffaelli, Lucie Rodriguez, Laura Gonzalez, Anette Johnsson, Constantin Habimana Mugabo, Tadepally Lakshmikanth, Petter Brodin

引用次数: 0

Abstract

We provide preliminary evidence that, also in children, Long coronavirus disease (COVID) may be characterized by a proinflammatory signature. Ten Long COVID patients, 7 convalescent subjects after COVID infection and 4 healthy controls were enrolled. When adjusted for sex, children with long COVID had statistically significant differences in the levels of Flt3L, CD5, uPA, CCL23, CD40 and TGFα. When adjusted for age, CCL23 levels remained statistically significant.

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儿童感染 SARS-CoV-2 后的细胞因子谱：初步研究结果

我们提供的初步证据表明，长冠状病毒病（COVID）在儿童中也可能具有促炎特征。我们招募了 10 名长冠状病毒病患者、7 名感染长冠状病毒后的康复者和 4 名健康对照者。如果对性别进行调整，长COVID患儿的Flt3L、CD5、uPA、CCL23、CD40和TGFα水平差异有统计学意义。根据年龄进行调整后，CCL23水平仍具有统计学意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pediatric Infectious Disease Journal 医学-传染病学

CiteScore

6.30

自引率

2.80%

发文量

566

审稿时长

2-4 weeks

期刊介绍： The Pediatric Infectious Disease Journal® (PIDJ) is a complete, up-to-the-minute resource on infectious diseases in children. Through a mix of original studies, informative review articles, and unique case reports, PIDJ delivers the latest insights on combating disease in children — from state-of-the-art diagnostic techniques to the most effective drug therapies and other treatment protocols. It is a resource that can improve patient care and stimulate your personal research.