Elliptical Halbach magnet and gradient modules for low-field portable magnetic resonance imaging.

IF 2.7 4区 医学 Q2 BIOPHYSICS
NMR in Biomedicine Pub Date : 2024-12-01 Epub Date: 2024-09-30 DOI:10.1002/nbm.5258
Fernando Galve, Eduardo Pallás, Teresa Guallart-Naval, Pablo García-Cristóbal, Pablo Martínez, José M Algarín, Jose Borreguero, Rubén Bosch, Francisco Juan-Lloris, José M Benlloch, Joseba Alonso
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引用次数: 0

Abstract

This study aims to develop methods to design the complete magnetic system for a truly portable MRI scanner for neurological and musculoskeletal (MSK) applications, optimized for field homogeneity, field of view (FoV), and gradient performance compared to existing low-weight configurations. We explore optimal elliptic-bore Halbach configurations based on discrete arrays of permanent magnets. In this way, we seek to improve the field homogeneity and remove constraints to the extent of the gradient coils typical of Halbach magnets. Specifically, we have optimized a tightly packed distribution of magnetic Nd2Fe14B cubes with differential evolution algorithms and a second array of shimming magnets with interior point and differential evolution methods. We have also designed and constructed an elliptical set of gradient coils that extend over the whole magnet length, maximizing the distance between the lobe centers. These are optimized with a target field method minimizing a cost function that considers also heat dissipation. We have employed the new toolbox to build the main magnet and gradient modules for a portable MRI scanner designed for point-of-care and residential use. The elliptical Halbach bore has semi-axes of 10 and 14& cm, and the magnet generates a field of 87& mT homogeneous down to 5700& ppm (parts per million) in a 20-cm diameter FoV; it weighs 216& kg and has a width of 65& cm and a height of 72& cm. Gradient efficiencies go up to around 0.8& mT/m/A, for a maximum of 12& mT/m within 0.5& ms with 15& A and 15& V amplifier. The distance between lobes is 28& cm, significantly increased with respect to other Halbach-based scanners. Heat dissipation is around 25& W at maximum power, and gradient deviations from linearity are below 20% in a 20-cm sphere. Elliptic-bore Halbach magnets enhance the ergonomicity and field distribution of low-cost portable MRI scanners, while allowing for full-length gradient support to increase the FoV. This geometry can be potentially adapted for a prospective low-cost whole-body technology.

用于低场便携式磁共振成像的椭圆形哈尔巴赫磁体和梯度模块。
本研究旨在开发用于神经和肌肉骨骼(MSK)应用的真正便携式磁共振成像扫描仪的全套磁系统设计方法,与现有的低重量配置相比,优化了磁场均匀性、视场(FoV)和梯度性能。我们探索了基于离散永磁阵列的最佳椭圆孔哈尔巴赫配置。这样,我们就能改善磁场均匀性,并消除对哈尔巴赫磁体典型梯度线圈范围的限制。具体来说,我们利用差分进化算法优化了紧密排列的磁性 Nd2Fe14B 立方体分布,并利用内点和差分进化方法优化了第二个垫片磁体阵列。我们还设计并建造了一组椭圆形梯度线圈,它们延伸至整个磁体长度,最大限度地增加了磁叶中心之间的距离。我们采用目标场方法对这些线圈进行了优化,使成本函数最小化,同时还考虑了散热问题。我们利用新工具箱为一台便携式核磁共振扫描仪构建了主磁体和梯度模块,该扫描仪设计用于医疗点和住宅。椭圆形哈尔巴赫孔的半轴分别为 10 厘米和 14 厘米,磁体在 20 厘米直径的 FoV 内产生 87& mT 的均匀磁场,最低可达 5700&ppm(百万分之一);它重 216&公斤,宽 65&厘米,高 72&厘米。梯度效率高达 0.8 mT/m/A,在 15A 和 15V 放大器的作用下,0.5 毫秒内的最大值为 12mT/m。叶片之间的距离为 28&厘米,与其他基于哈尔巴赫的扫描仪相比明显增加。最大功率时的散热量约为 25& W,在 20 厘米的球面上,梯度线性偏差低于 20%。椭圆孔哈尔巴赫磁体提高了低成本便携式磁共振成像扫描仪的人体工程学性能和磁场分布,同时允许全长梯度支持以增加视场角。这种几何形状可用于未来的低成本全身技术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
NMR in Biomedicine
NMR in Biomedicine 医学-光谱学
CiteScore
6.00
自引率
10.30%
发文量
209
审稿时长
3-8 weeks
期刊介绍: NMR in Biomedicine is a journal devoted to the publication of original full-length papers, rapid communications and review articles describing the development of magnetic resonance spectroscopy or imaging methods or their use to investigate physiological, biochemical, biophysical or medical problems. Topics for submitted papers should be in one of the following general categories: (a) development of methods and instrumentation for MR of biological systems; (b) studies of normal or diseased organs, tissues or cells; (c) diagnosis or treatment of disease. Reports may cover work on patients or healthy human subjects, in vivo animal experiments, studies of isolated organs or cultured cells, analysis of tissue extracts, NMR theory, experimental techniques, or instrumentation.
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