Ethanolic extraction and GC-MS analysis of antioxidant and anticancer bioactive compounds from Mentha arvensis and Aegle marmelos.

IF 1.9 3区化学 Q3 CHEMISTRY, APPLIED

Natural Product Research Pub Date : 2024-09-27 DOI:10.1080/14786419.2024.2406993

Reena V Mathai, Santosh Kumar Sar, Jayati Chatterjee Mitra, Manoj Kumar Jindal, Faming Wang

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Abstract

Bioactive components used to treat human ailments are abundant in medicinal plants. Mentha arvensis and Aegle marmelos have therapeutic properties due to the presence of many phytonutrients. Gas chromatography-mass spectrometry (GC-MS) was used to evaluate the properties of the antioxidant and anticancer bioactive components found in the ethanolic extracts of Mentha arvensis and Aegle marmelos leaves. The major constituents identified in the leaf extracts were octadecanoic acid, heptadecanoic acid, 15-methyl-9,12,15-octadecatrienoic acid, ethyl ester, hexadecanoic acid, neophytadiene, pentadecane, hexadecane, and 1-octadecanol. Some of these components have antibacterial, antioxidant, anticancer, and anti-inflammatory properties. Among the identified compounds, octadecanoic acid and n-hexadecanoic acid are pivotal for their anticancer and antioxidant effects. The GC-MS characterisation indicated the existence of abundant bioactive compounds, confirming their potential therapeutic activities. This study showed that the leaves of Mentha arvensis and Aegle marmelos could be used as novel sources of antioxidants and anticancer medicines.

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薄荷和芒柄菊中抗氧化和抗癌生物活性化合物的乙醇提取和气相色谱-质谱分析。

药用植物中含有大量用于治疗人类疾病的生物活性成分。薄荷（Mentha arvensis）和芒果（Aegle marmelos）因含有多种植物营养素而具有治疗功效。气相色谱-质谱法（GC-MS）被用来评估薄荷叶和芒柄菊叶乙醇提取物中抗氧化和抗癌生物活性成分的特性。经鉴定，叶提取物中的主要成分为十八酸、十七酸、15-甲基-9,12,15-十八碳三烯酸、乙酯、十六酸、新茶二烯、十五烷、十六烷和 1-十八醇。其中一些成分具有抗菌、抗氧化、抗癌和抗炎特性。在已鉴定的化合物中，十八酸和正十六酸的抗癌和抗氧化作用至关重要。气相色谱-质谱（GC-MS）表征表明存在丰富的生物活性化合物，证实了其潜在的治疗活性。这项研究表明，薄荷叶和芒果叶可作为抗氧化剂和抗癌药物的新来源。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Natural Product Research 化学-医药化学

CiteScore

5.10

自引率

9.10%

发文量

605

审稿时长

2.1 months

期刊介绍： The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds. The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal. Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section. All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.