Performance of applications of Ophytrium-containing mousse with or without shampoo in cats with pruritic and irritated skin: a multicentre prospective field trial.

IF 1.9 2区 农林科学 Q2 VETERINARY SCIENCES
Hélène Dropsy, Xavier De Jaeger, Alicia Cozar, Charlotte Billy, Aude Bressolin, Amaury Briand, Marion Debraine, Véronique Deschamps, Chiara Noli, Aude Puozzo-Barichard, Marina Gatellet
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Abstract

Objectives: This study aimed to evaluate the performance of a protocol in which topical products (DOUXO S3 CALM Shampoo and Mousse; Ceva Santé Animale) containing Ophytrium were applied to cats to help manage feline atopic syndrome (FAS).

Methods: A total of 23 client-owned cats with a history of FAS and presenting irritated skin and pruritus were recruited for this study. The cats were either shampooed or moussed on day 0 (D0) and then moussed every 48-72 h for 3 weeks. On D0, D7 and D21, clinical signs were assessed using the validated scoring system, Scoring Feline Allergic Dermatitis (SCORFAD). Pruritus was graded by the owner using an adapted dual visual analogue scale (Pruritus Visual Analog Scale for Cats [VAScat]). Veterinarians also assessed pruritus intensity and frequency, and provided a subjective assessment of global skin condition and of improvements in each cat's condition. On D21, all questionnaires were collected from both veterinarians and owners.

Results: Among the 19 cats that completed the study, the SCORFAD and VASmax (maximum value of VAScat, either scratching or licking) scores improved by ⩾50% in 63.2% and 38.9% of animals, respectively. Mean SCORFAD values decreased significantly between D0 and D21 (from 6.2 to 2.8, P <0.05). Similarly, mean VASmax values decreased significantly between D0 and D21 (from 7.4 to 4.3, P <0.05). Overall, veterinarians assessed the improvement as satisfactory, good or excellent in 18/19 (94.7%) cases. The protocol was considered efficient and practical by 18/19 (94.7%) and 19/19 (100%) owners, respectively, and the resulting good condition of skin and coat was emphasised by 15/19 (78.9%) owners.

Conclusions and relevance: This topical protocol with Ophytrium-containing mousse and shampoo was well tolerated. The products were effective in reducing skin irritation and discomfort quickly and significantly in cats with skin irritation and pruritus, yielding high satisfaction levels among both veterinarians and owners.

在皮肤瘙痒和过敏的猫咪身上涂抹或不涂抹香波的含 Ophytrium 的摩丝的效果:一项多中心前瞻性现场试验。
研究目的本研究旨在评估给猫咪使用含有奥菲他酮的外用产品(DOUXO S3 CALM香波和摩丝;Ceva Santé Animale)以帮助控制猫咪特应性综合征(FAS)的方案的效果:本研究共招募了 23 只客户饲养的猫,这些猫都有特应性综合征病史,并表现出皮肤过敏和瘙痒。这些猫在第 0 天(D0)接受洗发或涂抹,然后每隔 48-72 小时涂抹一次,持续 3 周。在第 0 天、第 7 天和第 21 天,使用经过验证的评分系统 "猫过敏性皮炎评分(SCORFAD)"对临床症状进行评估。猫瘙痒由猫主人使用改编的双重视觉模拟量表(猫瘙痒视觉模拟量表 [VAScat])进行分级。兽医也会评估瘙痒的强度和频率,并对每只猫的整体皮肤状况和病情改善情况进行主观评估。在第 21 天,兽医和猫主人收集了所有问卷:结果:在完成研究的 19 只猫咪中,63.2% 和 38.9% 的猫咪的 SCORFAD 和 VASmax(VAScat 的最大值,抓挠或舔食)得分分别提高了 ⩾50% 和 ⩾50%。SCORFAD的平均值在D0和D21之间显著下降(从6.2降至2.8,P P 结论和相关性:使用含Ophytrium的摩丝和洗发水的局部治疗方案具有良好的耐受性。这些产品能有效、快速、显著地减轻猫皮肤过敏和瘙痒症状,兽医和猫主人都非常满意。
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来源期刊
CiteScore
3.90
自引率
17.60%
发文量
254
审稿时长
8-16 weeks
期刊介绍: JFMS is an international, peer-reviewed journal aimed at both practitioners and researchers with an interest in the clinical veterinary healthcare of domestic cats. The journal is published monthly in two formats: ‘Classic’ editions containing high-quality original papers on all aspects of feline medicine and surgery, including basic research relevant to clinical practice; and dedicated ‘Clinical Practice’ editions primarily containing opinionated review articles providing state-of-the-art information for feline clinicians, along with other relevant articles such as consensus guidelines.
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