Vascular changes in the retinal capillary network in fellow eye of the patients with central retinal artery occlusion.

IF 1.4 4区医学 Q3 OPHTHALMOLOGY

International Ophthalmology Pub Date : 2024-09-26 DOI:10.1007/s10792-024-03304-5

Seyed Ali Tabatabaei, Zohre Ebrahimi, Mohammad Soleimani, Zahra Mahdizad, Mehrnaz Atighechian, Fatemeh Bazvand, Mohammadreza Mehrabi Bahar, Arash Mirzaei, Shakiba Dehghani

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引用次数: 0

Abstract

Background: We aimed to evaluate the retinal vascular changes in the superficial and deep retinal vascular networks in the fellow eye of patients with central retinal artery occlusion (CRAO) and compare them with controls using optical coherence tomography angiography (OCT-A).

Methods: In a cross-sectional study, 27 patients with CRAO and 189 normal controls were included. Ophthalmic examination and OCT-A images were performed on all participants.

Results: The total vascular density of the superficial capillary network in the 6-mm scan was significantly lower in the fellow eye of patients with CRAO than in the control group (p = 0.02). No significant difference was observed in the FAZ area of the affected eyes and their fellow eyes compared with the controls. Total vascular density at 300 microns around the fovea was lower in the fellow eye compared with the control group (p = 0.034).

Conclusions: The retinal vascular network changes in the fellow eyes of patients with CRAO suggest that persistent microvascular changes may be present before the onset of CRAO. This finding indicates that such changes could serve as an early diagnostic window for systemic vascular changes before catastrophic vascular events occur.

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视网膜中央动脉闭塞患者同侧眼视网膜毛细血管网的血管变化。

背景：我们旨在评估视网膜中央动脉闭塞（CRAO）患者同侧眼浅层和深层视网膜血管网络的变化，并使用光学相干断层血管造影（OCT-A）与对照组进行比较：在一项横断面研究中，纳入了 27 名 CRAO 患者和 189 名正常对照者。所有参与者均接受了眼科检查和 OCT-A 图像：结果：在 6 毫米扫描中，CRAO 患者同侧眼浅层毛细血管网的总血管密度明显低于对照组（P = 0.02）。与对照组相比，患眼及其同侧眼的FAZ区域未观察到明显差异。与对照组相比，同组患者眼窝周围 300 微米处的总血管密度较低（p = 0.034）：结论：CRAO 患者同侧眼视网膜血管网络的变化表明，持续性微血管变化可能在 CRAO 发病前就已存在。结论：CRAO 患者同侧眼视网膜血管网的变化表明，持续性微血管变化可能在 CRAO 发病前就已存在，这一发现表明，在灾难性血管事件发生前，这种变化可作为全身血管变化的早期诊断窗口。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Ophthalmology OPHTHALMOLOGY-

CiteScore

3.20

自引率

0.00%

发文量

451

期刊介绍： International Ophthalmology provides the clinician with articles on all the relevant subspecialties of ophthalmology, with a broad international scope. The emphasis is on presentation of the latest clinical research in the field. In addition, the journal includes regular sections devoted to new developments in technologies, products, and techniques.