pRESET thrombectomy device outcomes in patients with acute ischemic stroke: A systematic review and meta-analysis.

IF 1.7 4区医学 Q3 Medicine

Interventional Neuroradiology Pub Date : 2024-09-27 DOI:10.1177/15910199241286753

Abdelrahman M Hamouda, Mark Cwajna, Hassan Kobeissi, Nicholas Kendall, Tasnim Elgazzar, Sherief Ghozy, Waleed Brinjikji, David F Kallmes

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引用次数: 0

Abstract

Background: Many devices are used to perform mechanical thrombectomy in the setting of large vessel occlusion acute ischemic stroke. We sought to evaluate the efficacy and safety of pRESET stent-retriever systems.

Methods: We conducted a comprehensive systematic review and meta-analysis following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Relevant studies up to March 2024 were retrieved from PubMed, Scopus, Web of Science, and Embase databases.

Results: A total of 8 papers met the inclusion/exclusion criteria comprising a total of 1140 participants (average age 72.4 ± 11.9, female percentage (50%). Preintervention intravenous thrombolysis was utilized in 46.5% (range 32.9-65.4) of patients, with a median National Institute of Health Stroke Scale at presentation of 15 (range 0-38). The middle cerebral artery was the most commonly affected artery, with a prevalence of 76.4% (range 62.8-100). The pRESET stent-retriever systems demonstrated a first-passing effect rate of 53.4% [95% confidence interval [CI] 44.8; 61.7] and a final thrombolysis in cerebral infarction 2b-3 grade rate of 90.41% [95% CI 82.13; 95.08]. Ninety-day modified Rankin Scale (0-2) rate was 42.2% [95% CI 27.6; 58.4], and 90-day mortality rate was 15.1% [95% CI 9.8; 22.6]. Postintervention hemorrhage occurred at a rate of 28.6% [CI 17.2; 43.6].

Conclusion: Our systematic review and meta-analysis describes the efficacy of the pRESET stent retriever system in managing acute ischemic stroke patients. The pRESET device was found to have a similar safety and efficacy profile to other mechanical thrombectomy devices currently in use.

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pRESET血栓切除装置对急性缺血性脑卒中患者的疗效：系统回顾和荟萃分析。

背景：在大血管闭塞性急性缺血性卒中的情况下，许多设备都可用于进行机械血栓切除术。我们试图评估 pRESET 支架截流系统的有效性和安全性：我们按照《系统综述和荟萃分析首选报告项目》指南进行了全面的系统综述和荟萃分析。我们从 PubMed、Scopus、Web of Science 和 Embase 数据库中检索了截至 2024 年 3 月的相关研究：共有 8 篇论文符合纳入/排除标准，共有 1140 名参与者（平均年龄为 72.4±11.9 岁，女性占 50%）。46.5%（32.9-65.4）的患者采用了干预前静脉溶栓治疗，发病时美国国立卫生研究院卒中量表中位数为15（0-38）。大脑中动脉是最常受影响的动脉，患病率为 76.4%（范围 62.8-100）。pRESET支架-截流器系统的首次通过效果率为53.4%[95%置信区间[CI] 44.8; 61.7]，脑梗塞2b-3级最终溶栓率为90.41%[95% CI 82.13; 95.08]。90天改良Rankin量表（0-2）率为42.2% [95% CI 27.6; 58.4]，90天死亡率为15.1% [95% CI 9.8; 22.6]。干预后出血发生率为 28.6% [CI 17.2; 43.6]：我们的系统综述和荟萃分析描述了 pRESET 支架回取系统在治疗急性缺血性卒中患者方面的疗效。研究发现，pRESET 装置与目前使用的其他机械血栓切除装置具有相似的安全性和有效性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Interventional Neuroradiology 医学-核医学

CiteScore

2.80

自引率

11.80%

发文量

192

审稿时长

6-12 weeks

期刊介绍： Interventional Neuroradiology (INR) is a peer-reviewed clinical practice journal documenting the current state of interventional neuroradiology worldwide. INR publishes original clinical observations, descriptions of new techniques or procedures, case reports, and articles on the ethical and social aspects of related health care. Original research published in INR is related to the practice of interventional neuroradiology...