Retinal vascular changes after Silicon Oil removal in the Eye with Rhegmatogenous Retinal detachment.

IF 1.9 Q2 OPHTHALMOLOGY
Ali Salehi, Mohammad Malekahmadi, Abolfazl Karimi, Afsaneh Naderi Beni
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引用次数: 0

Abstract

Background: This study aims to examine vessel density changes in the optic nerve and macula following silicone oil removal (SOR) surgery in eyes with rhegmatogenous retinal detachment (RRD) at different time points by Optical Coherence Tomography Angiography (OCTA) in compared to the contralateral eye.

Methods: A total of 43 eyes from 43 patients with silicone oil in their eyes for 3-9 months underwent OCT-A using AngioVue and optic disc-associated vessel density (VD) and thickness, macular-associated VD and thickness, Foveal avascular zone (FAZ) area, FAZ perimeter (PERIM), Acircularity index (AI), vessel density within a 300 μm wide region of the FAZ were compared between eyes. OCTA scans were performed one week before SOR and one month and three months after SOR.

Results: The mean age of participants was 52.8 years (SD = 15.85) and a median visual acuity was 0.8 (range: 0.5-1.0). Notably, male participants constituted 67.4% of the sample. The preoperative mean value BCVA (logMAR) of patients was 0.73, and 3 months post-oil removal was 0.7727. Regarding optic disc parameters, RNFL thickness and vessel density (VD) measurements Peripapillary, whole disc, inside disc, and Disc Angio (superior, Nasal, inferior, temporal) did not change. In analyzing macular thickness parameters, all of them (Whole and Fovea, parafoveal, and Perifovea) remained unchanged. Examining macular vessel density parameters revealed no significant changes across superficial and deep retinal layers. Finally, the comparison of the foveal avascular zone (FAZ) area and flow density (FD) parameters demonstrated consistent measurements with non-significant alterations observed in FAZ size (p = 0.6) and FD values (p = 0.49) over the monitored duration.

Conclusion: There was no change in peripapillary VD and macular vessel density of the superficial capillary plexus (SCP) and deep capillary plexus (DCP) after silicone oil removal. FAZ and full retinal thickness  remained stable 3 month after SOR.  Clinical trial number: Not applicable.

流变性视网膜脱离患者去除硅油后视网膜血管的变化。
背景:本研究旨在通过光学相干断层扫描血管造影(OCTA)检查流变性视网膜脱离(RRD)患者在不同时间点进行硅油摘除(SOR)手术后视神经和黄斑的血管密度变化,并与对侧眼进行比较:方法: 共有 43 名患者的 43 只眼睛在眼内涂抹硅油 3-9 个月后,使用 AngioVue 进行了 OCT-A 扫描,比较了两只眼睛的视盘相关血管密度(VD)和厚度、黄斑相关血管密度(VD)和厚度、眼窝无血管区(FAZ)面积、FAZ 周长(PERIM)、弧度指数(AI)、FAZ 300 μm 宽区域内的血管密度。在 SOR 前一周、SOR 后一个月和三个月分别进行了 OCTA 扫描:参与者的平均年龄为 52.8 岁(SD = 15.85),视力中位数为 0.8(范围:0.5-1.0)。值得注意的是,男性参与者占样本的 67.4%。患者术前的 BCVA 平均值(logMAR)为 0.73,去油后 3 个月的平均值为 0.7727。在视盘参数方面,RNFL 厚度和血管密度(VD)的测量结果毛细血管周围、整个视盘、视盘内部和视盘血管(上、鼻、下、颞)均无变化。在分析黄斑厚度参数时,所有参数(整个黄斑和眼窝、眼窝旁和眼窝周围)均保持不变。黄斑血管密度参数显示,视网膜浅层和深层均无明显变化。最后,对眼窝无血管区(FAZ)面积和血流密度(FD)参数的比较显示,在监测期间,FAZ 大小(p = 0.6)和 FD 值(p = 0.49)的测量结果一致,无明显变化:结论:去除硅油后,毛细血管浅丛(SCP)和毛细血管深丛(DCP)的毛细血管周密度和黄斑血管密度没有变化。SOR 3 个月后,FAZ 和全视网膜厚度保持稳定。 临床试验编号:不适用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.50
自引率
4.30%
发文量
81
审稿时长
19 weeks
期刊介绍: International Journal of Retina and Vitreous focuses on the ophthalmic subspecialty of vitreoretinal disorders. The journal presents original articles on new approaches to diagnosis, outcomes of clinical trials, innovations in pharmacological therapy and surgical techniques, as well as basic science advances that impact clinical practice. Topical areas include, but are not limited to: -Imaging of the retina, choroid and vitreous -Innovations in optical coherence tomography (OCT) -Small-gauge vitrectomy, retinal detachment, chromovitrectomy -Electroretinography (ERG), microperimetry, other functional tests -Intraocular tumors -Retinal pharmacotherapy & drug delivery -Diabetic retinopathy & other vascular diseases -Age-related macular degeneration (AMD) & other macular entities
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