Cannabinoids and the heart-a psychiatrist's perspective.

IF 1.1 4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS
Herz Pub Date : 2024-09-27 DOI:10.1007/s00059-024-05273-y
Johannes Kramer, Gabi Koller, Oliver Pogarell
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引用次数: 0

Abstract

The partial legalization of cannabis in Germany in 2024 will affect both medical and recreational use of cannabis. Tetrahydrocannabinol (THC), the main psychoactive component of the cannabis plant, influences heart rate and blood pressure through the endocannabinoid system. Acute and chronic use can pose cardiovascular risks. There is evidence of a link between cannabis use and cardiovascular events such as stroke and myocardial infarction, although studies show conflicting results. The non-psychoactive cannabidiol (CBD) could have anti-inflammatory and antioxidant effects. Smoking cannabis poses additional cardiovascular risks similar to tobacco. Given these risks, cardiologists should routinely ask their patients about possible cannabis use and inform them about the potential cardiovascular dangers. The article also highlights the psychiatric risks of cannabis use, including dependence and psychosis, and emphasizes the need for interdisciplinary collaboration between cardiologists and psychiatrists to effectively manage cannabis-related health problems.

大麻素与心脏--精神科医生的视角。
德国将于 2024 年部分实现大麻合法化,这将对大麻的医疗和娱乐使用产生影响。大麻植物的主要精神活性成分四氢大麻酚(THC)会通过内源性大麻素系统影响心率和血压。急性和慢性吸食大麻都会对心血管造成危害。有证据表明,吸食大麻与中风和心肌梗塞等心血管事件有关,但研究结果相互矛盾。非精神活性的大麻二酚(CBD)具有抗炎和抗氧化作用。吸食大麻会带来与烟草类似的额外心血管风险。鉴于这些风险,心脏病专家应定期询问病人是否可能吸食大麻,并告知他们潜在的心血管危险。文章还强调了使用大麻的精神风险,包括依赖性和精神病,并强调心脏科医生和精神科医生需要进行跨学科合作,以有效管理与大麻相关的健康问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Herz
Herz 医学-心血管系统
CiteScore
3.00
自引率
5.90%
发文量
61
审稿时长
4-8 weeks
期刊介绍: Herz is the high-level journal for further education for all physicians interested in cardiology. The individual issues of the journal each deal with specific topics and comprise review articles in English and German written by competent and esteemed authors. They provide up-to-date and comprehensive information concerning the speciality dealt with in the issue. Due to the fact that all relevant aspects of the pertinent topic of an issue are considered, an overview of the current status and progress in cardiology is presented. Reviews and original articles round off the spectrum of information provided.
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