Frequency of Atopic Dermatitis and Psoriasis in the Elderly: Cross-Sectional Findings from the German AugUR Study.

IF 3 3区医学 Q2 DERMATOLOGY

Dermatology Pub Date : 2024-09-27 DOI:10.1159/000541590

Karl Philipp Drewitz, Klaus J Stark, Martina E Zimmermann, Iris M Heid, Christian J Apfelbacher

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Abstract

Introduction: Atopic dermatitis (AD) and psoriasis appear to affect 2-3% (lifetime prevalence) people worldwide. However, there are little epidemiological data on the prevalence of those two chronic inflammatory skin diseases in the elderly. The aim of this study was to provide frequency estimates of AD and psoriasis obtained from an elderly population in Germany.

Methods: We examined baseline data from the AugUR study, a cohort study focusing on an aging population in the city and the vicinity of Regensburg, Germany. We estimated raw frequencies of physician-diagnosed AD and psoriasis from participants' self-reports in personal interviews. These frequencies were adjusted to reflect the demographic distribution of the Bavarian population, considering both sex and age groupings spanning 5 or 10 years and reported with 95% confidence interval (CI).

Results: Data from 1,133 participants aged 70-95 (median age 76.7 years, 45.1% women) were available for analysis. Physician-diagnosed AD was reported by 3.3% (95% CI: 2.3-4.5) of participants (2.4% from men, 4.3% from women) and 5.6% (95% CI: 4.3-7.1%) reported physician-diagnosed psoriasis (6.6% in men, 4.3% in women). Age- and sex-standardized frequency estimates for AD were 3.4% (95% CI: 2.4-4.6, 2.6% in men, 4.3% in women) and 5.3% for psoriasis (95% CI: 4.1-6.8, 6.3% in men and 4.1% in women).

Conclusion: This study indicates a lower than previously reported lifetime prevalence of AD (3.4% vs. 8-10%) and a higher one regarding psoriasis (5.3% vs. 2-4%) in highly aged individuals. More epidemiological research in elderly populations using validated physician diagnoses is desirable.

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老年人特应性皮炎和银屑病的发病率--德国 AugUR 研究的横断面结果。

导言特应性皮炎（AD）和银屑病似乎影响着全世界 2-3%（终生患病率）的人。然而，有关这两种慢性炎症性皮肤病在老年人中发病率的流行病学数据却很少。本研究的目的是提供德国老年人口中 AD 和银屑病发病率的估计值。方法我们检查了 AugUR 研究的基线数据，这是一项针对德国雷根斯堡附近老龄人口的队列研究（共有 1,133 名参与者，中位年龄为 76.7 岁，45% 为女性）。我们根据参与者在个人访谈中的自我报告，估算出医生诊断为注意力缺失症和银屑病的原始频率。我们对这些频率进行了调整，以反映巴伐利亚州的人口分布情况，同时考虑到跨越 5 年或 10 年的性别和年龄分组。结果有 1,133 名 70-95 岁的参与者（45.1% 为女性）的数据可供分析。3.3%的参与者（男性 2.4%，女性 4.3%）被医生诊断为注意力缺失症，5.6%（95%-CI：4.3-7.1%）的参与者（男性 6.6%，女性 4.3%）被医生诊断为银屑病。按年龄和性别标准化的发病频率估计值为：注意力缺失症为 3.4%（95%-CI：2.4-4.6，男性为 2.6%，女性为 4.3%），银屑病为 5.3%（95%-CI：4.1-6.8，男性为 6.3%，女性为 4.1%）。结论本研究表明，在高龄人群中，注意力缺失症的终生患病率（3.4% 对 8-10%）和银屑病的终生患病率（5.3% 对 2-4%）均低于之前的报道。我们希望在老年人群中开展更多的流行病学研究，并使用有效的医生诊断方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Dermatology 医学-皮肤病学

CiteScore

6.40

自引率

2.90%

发文量

审稿时长

1 months

期刊介绍： Published since 1893, ''Dermatology'' provides a worldwide survey of clinical and investigative dermatology. Original papers report clinical and laboratory findings. In order to inform readers of the implications of recent research, editorials and reviews prepared by invited, internationally recognized scientists are regularly featured. In addition to original papers, the journal publishes rapid communications, short communications, and letters to ''Dermatology''. ''Dermatology'' answers the complete information needs of practitioners concerned with progress in research related to skin, clinical dermatology and therapy. The journal enjoys a high scientific reputation with a continually increasing impact factor and an equally high circulation.