68 Ga-FAPI and 18 F-FDG PET/CT Imaging in Langerhans Cell Histiocytosis for Recurrence and Therapeutic Response Assessment.

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2024-11-01 Epub Date: 2024-09-25 DOI:10.1097/RLU.0000000000005476

Mengna Liu, Ranbie Tang, Xi Chen, Liang Cai, Zhanwen Huang

引用次数: 0

Abstract

Abstract: A 2-and-a-half-year-old boy with a previous history of Langerhans cell histiocytosis reached remission as assessed by 18 F-FDG PET/CT. Routine follow-up 18 F-FDG PET/CT revealed the appearance of new bone lesions in the right scapula and right ischium with abnormal FDG activity 3 months after the end of treatment, and Langerhans cell histiocytosis recurrence was considered. Meanwhile, these lesions also showed increased FAPI uptake. After adjusting the chemotherapy regimen, both FDG and FAPI uptake almost disappeared in these lesions.

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用于朗格汉斯细胞组织细胞增生症复发和治疗反应评估的 68Ga-FAPI 和 18F-FDG PET/CT 成像。

摘要：一名曾患朗格汉斯细胞组织细胞增生症的两岁半男孩经18F-FDG PET/CT检查后病情得到缓解。常规随访 18F-FDG PET/CT 发现，治疗结束 3 个月后，右肩胛骨和右喙突出现新的骨病变，且 FDG 活性异常，考虑朗格汉斯细胞组织细胞增生症复发。同时，这些病灶也显示出 FAPI 摄取增加。调整化疗方案后，这些病灶的 FDG 和 FAPI 摄取几乎消失。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.