Magnetic resonance imaging and clinicopathological findings of primary hepatic angiosarcoma.

IF 2.3 3区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Abdominal Radiology Pub Date : 2024-09-21 DOI:10.1007/s00261-024-04592-2

Jingwen Zhang, Jianming Cai, Cheng Yan, Mingzi Gao, Jing Han, Mingxin Zhang, Hailong Yu, Mengmeng Zhang, Changchun Liu, Jinghui Dong, Liqin Zhao

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引用次数: 0

Abstract

Purpose: To investigate the magnetic resonance imaging (MRI) and clinicopathological features of primary hepatic angiosarcoma (PHA) and enhance preoperative diagnosis.

Methods: MRI and clinicopathological information of 12 cases proved PHA were reviewed. Summarize the MRI characteristics of PHA combined with literature reviews.

Results: Among 12 cases (6 males and 6 females; age range, 23-70 years; mean, 53.3 years), one presented as a large mass, two as a diffuse infiltrating tumor, and nine as a mixed pattern of large masses with multiple nodules, all involving both lobes of the liver and ranging from 0.1 cm to 11 cm in diameter. A total of 63 lesions were analyzed, including 21 masses and 42 nodules. 13 masses (61.9%) demonstrated intratumoral hemorrhage. 18 masses (85.7%) demonstrated heterogeneous patchy, ring-shaped, septate, or irregular shaped enhancing foci on late arterial phase (LAP). On dynamic contrast-enhanced MRI (DCE-MRI), 14 masses (66.7%) showed a centripetal or centrifugal pattern of incomplete progressive enhancement. 6 nodules (14.3%) appeared intratumoral hemorrhage. 31 nodules (73.8%) showed no enhancing foci on LAP images and 27 nodules (64.3%) showed enhancement pattern of complete filling, either centripetal or centrifugal pattern. Moreover, 12 cases (100%) exhibited prominent vessels within or adjacent to at least one lesion.

Conclusion: PHA exhibits diverse appearances on MRI. Typical MRI signs include multifoci with intratumoral hemorrhage, prominent vessels within or adjacent to the foci, as well as varied degrees of progressive enhancement with incomplete filling in dominant masses of PHA.

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原发性肝血管肉瘤的磁共振成像和临床病理结果。

目的：研究原发性肝血管肉瘤（PHA）的磁共振成像（MRI）和临床病理特征，加强术前诊断：方法：回顾性分析12例证实为PHA的病例的磁共振成像和临床病理资料。结合文献综述总结PHA的MRI特征：12例病例（6男6女；年龄23-70岁；平均53.3岁）中，1例表现为巨大肿块，2例表现为弥漫浸润性肿瘤，9例表现为巨大肿块与多发结节混合型，均累及肝脏两叶，直径从0.1厘米到11厘米不等。共分析了 63 个病灶，包括 21 个肿块和 42 个结节。13个肿块（61.9%）显示有瘤内出血。18个肿块（85.7%）在晚期动脉相（LAP）上显示出异质斑块状、环状、隔膜状或不规则形状的增强灶。在动态对比增强磁共振成像（DCE-MRI）上，14 个肿块（66.7%）呈向心性或离心性不完全进行性增强模式。6个结节（14.3%）出现瘤内出血。31 个结节（73.8%）在 LAP 图像上无增强灶，27 个结节（64.3%）呈向心性或离心性完全充盈增强模式。此外，12 个病例（100%）至少有一个病灶内部或邻近有突出的血管：结论：PHA 在 MRI 上的表现多种多样。典型的 MRI 表现包括伴有瘤内出血的多发病灶、病灶内或邻近病灶的突出血管，以及不同程度的进行性强化，PHA 优势团块的不完全充盈。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Abdominal Radiology Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

5.20

自引率

8.30%

发文量

334

期刊介绍： Abdominal Radiology seeks to meet the professional needs of the abdominal radiologist by publishing clinically pertinent original, review and practice related articles on the gastrointestinal and genitourinary tracts and abdominal interventional and radiologic procedures. Case reports are generally not accepted unless they are the first report of a new disease or condition, or part of a special solicited section. Reasons to Publish Your Article in Abdominal Radiology: · Official journal of the Society of Abdominal Radiology (SAR) · Published in Cooperation with: European Society of Gastrointestinal and Abdominal Radiology (ESGAR) European Society of Urogenital Radiology (ESUR) Asian Society of Abdominal Radiology (ASAR) · Efficient handling and Expeditious review · Author feedback is provided in a mentoring style · Global readership · Readers can earn CME credits