A clinical evaluation of robotic-assisted radical prostatectomy (RARP) in located prostate cancer: A systematic review and network meta-analysis

IF 5.5 2区医学 Q1 HEMATOLOGY

Critical reviews in oncology/hematology Pub Date : 2024-09-25 DOI:10.1016/j.critrevonc.2024.104514

Meng-Yao Xu , Na Zeng , Sheng Ma , Zi-Jin Hua , Si-Han Zhang , Ji-Cheng Xiang , Yi-Fan Xiong , Zhi-Yu Xia , Jian-Xuan Sun , Chen-Qian Liu , Jin-Zhou Xu , Ye An , Shao-Gang Wang , Qi Dong Xia

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引用次数: 0

Abstract

Prostate cancer (PCa) is a prevalent malignant tumor affecting the male reproductive system and there are mainly three widely accepted PCa surgery types in current clinical treatment: open radical prostatectomy (ORP), laparoscopic radical prostatectomy (LRP) and robot-assisted radical prostatectomy (RARP). Here, we aimed to evaluate the clinical effect of RARP for PCa patients compared with ORP and LRP based on the context of PCa encompass two dimensions: oncological outcomes (biochemical recurrence (BCR) and positive surgical margin (PSM)) and functional outcomes (urinary continence and recovery of erectile function) in this network meta-analysis (NMA). PubMed, Embase and Cochrane databases were systematically searched in January 7, 2024. 4 randomized controlled trials (RCTs) and 72 non-RCTs were included. RARP displayed significant positive effect on lower BCR and better recovery of erectile function but no significant differences existed among three surgery types for PSM and urinary continence.

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机器人辅助前列腺癌根治术（RARP）的临床评估：系统综述与网络 Meta 分析》。

前列腺癌（PCa）是影响男性生殖系统的一种常见恶性肿瘤，目前临床上广泛接受的PCa手术主要有三种：开放性前列腺癌根治术（ORP）、腹腔镜前列腺癌根治术（LRP）和机器人辅助前列腺癌根治术（RARP）。在此，我们旨在通过网络荟萃分析（NMA），根据PCa的两个方面：肿瘤学结局（生化复发（BCR）和手术切缘阳性（PSM））和功能性结局（尿失禁和勃起功能恢复），评估RARP与ORP和LRP相比对PCa患者的临床效果。2024 年 1 月 7 日，对 PubMed、Embase 和 Cochrane 数据库进行了系统检索。共纳入 4 项随机对照试验 (RCT) 和 72 项非 RCT 试验。RARP对降低BCR和更好地恢复勃起功能有明显的积极作用，但三种手术类型在PSM和尿失禁方面没有明显差异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Critical reviews in oncology/hematology 医学-血液学

CiteScore

11.00

自引率

3.20%

发文量

213

审稿时长

55 days

期刊介绍： Critical Reviews in Oncology/Hematology publishes scholarly, critical reviews in all fields of oncology and hematology written by experts from around the world. Critical Reviews in Oncology/Hematology is the Official Journal of the European School of Oncology (ESO) and the International Society of Liquid Biopsy.