Considerations for Big Data management in pharmaceutical manufacturing

IF 8 2区工程技术 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Current Opinion in Chemical Engineering Pub Date : 2024-09-28 DOI:10.1016/j.coche.2024.101051

Jayanti Das , Adam C Fisher , Lisa Hughey , Thomas F O’Connor , Vidya Pai , Cinque Soto , John Wan

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引用次数: 0

Abstract

Big Data technologies are advancing the manufacturing of drug and biological products. Such technologies include innovative software and computational methods for data storage, mining, and analytics. Increasingly vast, complex data sets are being produced by advanced manufacturing processes and sensors for statistical analysis and decision-making. Implementing Big Data technologies, however, can introduce new challenges for organizations in areas of data generation, architecture, and security. Big Data management includes implementing robust storage, complex data integration, and state-of-the-art analysis software. Upholding data integrity and security might require designing a modernized risk-based framework plan for the organization. Once these challenges are successfully addressed, the incorporation of Big Data technologies into pharmaceutical manufacturing is expected to enable more efficient production, lower costs, and greater quality control, resulting in a stronger global pharmaceutical supply chain.

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制药业大数据管理的注意事项

大数据技术正在推动药物和生物产品的生产。这些技术包括用于数据存储、挖掘和分析的创新软件和计算方法。先进的制造流程和传感器正在产生越来越庞大、复杂的数据集，用于统计分析和决策。然而，实施大数据技术会在数据生成、架构和安全方面给企业带来新的挑战。大数据管理包括实施强大的存储、复杂的数据集成和最先进的分析软件。维护数据完整性和安全性可能需要为组织设计一个现代化的基于风险的框架计划。一旦成功应对这些挑战，将大数据技术融入制药业有望提高生产效率、降低成本和加强质量控制，从而加强全球制药供应链。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Opinion in Chemical Engineering BIOTECHNOLOGY & APPLIED MICROBIOLOGYENGINE-ENGINEERING, CHEMICAL

CiteScore

12.80

自引率

3.00%

发文量

114

期刊介绍： Current Opinion in Chemical Engineering is devoted to bringing forth short and focused review articles written by experts on current advances in different areas of chemical engineering. Only invited review articles will be published. The goals of each review article in Current Opinion in Chemical Engineering are: 1. To acquaint the reader/researcher with the most important recent papers in the given topic. 2. To provide the reader with the views/opinions of the expert in each topic. The reviews are short (about 2500 words or 5-10 printed pages with figures) and serve as an invaluable source of information for researchers, teachers, professionals and students. The reviews also aim to stimulate exchange of ideas among experts. Themed sections: Each review will focus on particular aspects of one of the following themed sections of chemical engineering: 1. Nanotechnology 2. Energy and environmental engineering 3. Biotechnology and bioprocess engineering 4. Biological engineering (covering tissue engineering, regenerative medicine, drug delivery) 5. Separation engineering (covering membrane technologies, adsorbents, desalination, distillation etc.) 6. Materials engineering (covering biomaterials, inorganic especially ceramic materials, nanostructured materials). 7. Process systems engineering 8. Reaction engineering and catalysis.