Les patients hospitalisés en réanimation pour un syndrome coronarien aigu de 2012 à 2021 : une étude rétrospective monocentrique

IF 0.3 Q4 Medicine

Annales de cardiologie et d'angeiologie Pub Date : 2024-09-26 DOI:10.1016/j.ancard.2024.101799

A. Yesiloz , S. Sanchez , H. Mesrar , J. Chrusciel , M. Dacunka , F. Raoul , G. Simon , D. Metz , L. Chapoutot

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Abstract

Introduction

Acute Coronary Syndrome (ACS) are one of the main causes of mortality in France. Patients presenting with ACS are typically hospitalized in a specialized cardiology ward. The main objective of this study was to describe, characterize and evaluate the outcome of patients hospitalized for ACS in a generalist intensive care unit (rather than a cardiac care unit).

Methods

This was a retrospective study. Our population consisted of ACS patients admitted to an intensive care unit in a hospital center (Centre Hospitalier de Troyes) between 2012 and 2021. All patients admitted for ACS to the intensive care unit and who underwent coronary angiography were included.

Results

In 10 years, 104 patients, or 3.8% of ACS patients who underwent coronary angiography were admitted to intensive care. The majority were admitted after recovered cardiac arrest (72%) and were in cardiogenic shock (68%), accounting for a high in-hospital mortality (45.2%). In-hospital mortality was 45.2%. In multivariate analysis, the GRACE score was associated with in-hospital mortality (OR for each additional point = 1.024, 95% confidence interval 1.006–1.045, p = 0.01). Among the survivors, 88% had good neurological function when leaving the hospital.

Discussion

Mortality of ACS patients in intensive care was close to 50%. However, the neurological prognosis of the surviving patients was good. This population is rarely mentioned in the literature, and deserves to be evaluated by multicenter, prospective registries, with a view to improving management and prognosis.

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2012 年至 2021 年因急性冠状动脉综合征在重症监护室住院的患者：一项单中心回顾性研究

导言急性冠状动脉综合征（ACS）是法国人死亡的主要原因之一。急性冠状动脉综合征患者通常在心脏病专科病房住院治疗。本研究的主要目的是描述、描述和评估在普通重症监护病房（而非心脏监护病房）住院的急性冠状动脉综合征患者的预后。研究对象包括2012年至2021年间在一家医院中心（特鲁瓦中心医院）重症监护室住院的ACS患者。结果 10年间，有104名患者（占接受冠状动脉造影术的ACS患者的3.8%）入住重症监护室。大多数患者是在心脏骤停（72%）和心源性休克（68%）后入院的，因此院内死亡率较高（45.2%）。院内死亡率为 45.2%。在多变量分析中，GRACE评分与院内死亡率相关（每增加一分的OR=1.024，95%置信区间为1.006-1.045，P=0.01）。讨论重症监护中的 ACS 患者死亡率接近 50%。然而，存活患者的神经系统预后良好。这一人群在文献中很少提及，值得通过多中心、前瞻性登记进行评估，以改善管理和预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annales de cardiologie et d'angeiologie 医学-外周血管病

CiteScore

0.60

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Organe scientifique de référence fondé en 1951, les Annales de cardiologie et d''angéiologie abordent tous les domaines qui intéressent quotidiennement les cardiologues et les angéiologues praticiens : neurologie et radiologie vasculaires, hémostase, diabétologie, médecine interne, épidémiologie et prévention. Les Annales de cardiologie et d''angéiologie sont indexées aux grandes bases de données et publient rapidement, et en conformité avec les normes internationales de publication scientifique, des articles en français sur la pathologie cardiaque.