Possible Transformation of Pseudotumor to Synovial Sarcoma in a Failed Metal-on-Metal Total Hip Arthroplasty

IF 1.5 Q3 ORTHOPEDICS

Arthroplasty Today Pub Date : 2024-09-26 DOI:10.1016/j.artd.2024.101408

Victor Shen BS , Reed Andrews MD , Odion Binitie MD , Brian T. Palumbo MD

引用次数: 0

Abstract

Adverse local tissue reaction (ALTR) from the release of chromium and cobalt ions in metal-on-metal total hip arthroplasty (MoM THA) is a well-reported complication, but there is little evidence suggesting that this inflammatory reaction causes malignancy. We present a 69-year-old female with MoM THA who developed synovial sarcoma (SS). She underwent mass resection and revision THA. Postoperative pathologic analysis revealed the unanticipated diagnosis of SS. She subsequently underwent chemotherapy, sarcoma resection, and endoprosthetic reconstruction. We hypothesize that the SS developed from an ALTR in the setting of failed MoM THA. Given the paucity of data on possible malignant transformation of an ALTR to SS, we advise surgeons to consider potential malignancies when diagnosing ALTR in the setting of failed MoM THA bearings.

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金属对金属全髋关节置换术失败者的假瘤可能转变为滑膜肉瘤

金属全髋关节置换术（MoM THA）中铬和钴离子的释放引起的局部组织不良反应（ALTR）是一种报道较多的并发症，但很少有证据表明这种炎症反应会导致恶性肿瘤。我们为您介绍一位 69 岁的女性患者，她曾接受过金属全髋关节置换术（MoM THA），但后来患上了滑膜肉瘤（SS）。她接受了肿块切除术和翻修型 THA。术后病理分析表明，她被意外诊断为滑膜肉瘤。她随后接受了化疗、肉瘤切除和假体内重建。我们推测，SS是在MoM THA失败的情况下由ALTR发展而来的。鉴于有关 ALTR 可能恶变为 SS 的数据较少，我们建议外科医生在确诊 ALTR 和 MoM THA 支架植入失败时考虑潜在的恶性肿瘤。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Arthroplasty Today Medicine-Surgery

CiteScore

2.90

自引率

0.00%

发文量

258

审稿时长

40 weeks

期刊介绍： Arthroplasty Today is a companion journal to the Journal of Arthroplasty. The journal Arthroplasty Today brings together the clinical and scientific foundations for joint replacement of the hip and knee in an open-access, online format. Arthroplasty Today solicits manuscripts of the highest quality from all areas of scientific endeavor that relate to joint replacement or the treatment of its complications, including those dealing with patient outcomes, economic and policy issues, prosthetic design, biomechanics, biomaterials, and biologic response to arthroplasty. The journal focuses on case reports. It is the purpose of Arthroplasty Today to present material to practicing orthopaedic surgeons that will keep them abreast of developments in the field, prove useful in the care of patients, and aid in understanding the scientific foundation of this subspecialty area of joint replacement. The international members of the Editorial Board provide a worldwide perspective for the journal''s area of interest. Their participation ensures that each issue of Arthroplasty Today provides the reader with timely, peer-reviewed articles of the highest quality.