Zirconium-doped zinc nanocomposites (ZDZN): Preparation, characterization, and evaluation of antibacterial activity

IF 3.2 4区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Journal of the Indian Chemical Society Pub Date : 2024-09-18 DOI:10.1016/j.jics.2024.101386

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Abstract

The present study focuses on zirconium-doped zinc nanocomposites (ZDZN), representing a novel class of materials with antibacterial and antifungal properties. This work involves the preparation, characterization, and evaluation of the antibacterial activity of ZDZN. Zinc oxide nanoparticles were doped with varying concentrations of zirconium ions to create nanocomposites using a simple precipitation technique. The structural, morphological, and chemical properties were investigated using EDS, TEM, SEM, and XRD analyses. The results indicated the successful incorporation of zirconium ions into the lattice of zinc oxide nanoparticles, resulting in nanocomposites with well-defined shapes and compositions. Agar diffusion studies were conducted to assess the antibacterial activities of the nanocomposites against various bacterial and fungal species. The findings revealed that ZDZN exhibited superior antibacterial activity compared to pure zinc oxide nanoparticles, attributed to the concentration-dependent effect of the zirconium dopant. Furthermore, the nanocomposites demonstrated excellent biocompatibility and stability, making them highly suitable for applications in biomedical devices and antimicrobial coatings.

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掺锆锌纳米复合材料（ZDZN）：制备、表征和抗菌活性评估

本研究的重点是掺锆锌纳米复合材料（ZDZN），它是一类具有抗菌和抗真菌特性的新型材料。这项工作涉及 ZDZN 的制备、表征和抗菌活性评估。采用简单的沉淀技术，在氧化锌纳米粒子中掺入不同浓度的锆离子，从而制备出纳米复合材料。使用 EDS、TEM、SEM 和 XRD 分析法研究了纳米复合材料的结构、形态和化学特性。结果表明，锆离子成功地融入了氧化锌纳米粒子的晶格中，从而产生了具有明确形状和成分的纳米复合材料。琼脂扩散研究评估了纳米复合材料对各种细菌和真菌的抗菌活性。研究结果表明，与纯氧化锌纳米粒子相比，ZDZN 具有更高的抗菌活性，这归因于锆掺杂剂的浓度依赖效应。此外，纳米复合材料还表现出优异的生物相容性和稳定性，因此非常适合应用于生物医学设备和抗菌涂层。

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来源期刊

Journal of the Indian Chemical Society 化学-化学综合

CiteScore

3.50

自引率

7.70%

发文量

492

审稿时长

3-8 weeks

期刊介绍： The Journal of the Indian Chemical Society publishes original, fundamental, theorical, experimental research work of highest quality in all areas of chemistry, biochemistry, medicinal chemistry, electrochemistry, agrochemistry, chemical engineering and technology, food chemistry, environmental chemistry, etc.