The incidence of sudden unexpected death in epilepsy (SUDEP) in the Republic of Ireland

IF 2.7 3区医学 Q2 CLINICAL NEUROLOGY

Seizure-European Journal of Epilepsy Pub Date : 2024-09-10 DOI:10.1016/j.seizure.2024.09.006

Yvonne Langan , Ena Lynn

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引用次数: 0

Abstract

Background

The incidence of sudden unexpected death in epilepsy (SUDEP) in Ireland has previously been studied in only a small geographical area. Our aim was to calculate an incidence rate for the whole of the Republic of Ireland in 2019.

Methods

All deaths referred to the coroner in 2019 were examined. Those with a history of possible epilepsy were noted and subjected to a more detailed assessment. Cases fulfilling the definition of definite SUDEP were identified. The incidence of SUDEP was calculated using the population of the Republic of Ireland in 2019 and the known prevalence of epilepsy in Ireland.

Results

Thirty-three cases of definite SUDEP were identified in the Republic of Ireland in 2019. The estimated incidence of SUDEP in the epilepsy population as a whole was 0.7/1000(0.46 – 0.94) person years. This may be a conservative estimate. More men than women were identified, and most individuals were found dead at home. SUDEP was mentioned on the death certificate in only 52 % of cases.

Conclusion

This is the first nationwide study of SUDEP incidence in Ireland and provides an incidence rate in keeping with other populations. This work demonstrates that the interrogation of coronial records is a useful way to monitor epilepsy mortality albeit with certain limitations.

查看原文本刊更多论文

爱尔兰共和国癫痫意外猝死（SUDEP）的发生率

背景爱尔兰癫痫意外猝死（SUDEP）的发病率此前仅在一小部分地区进行过研究。我们的目的是计算出2019年爱尔兰共和国全国的发病率。方法对2019年提交给验尸官的所有死亡病例进行检查。我们注意到那些可能有癫痫病史的死亡病例，并对其进行了更详细的评估。确定符合明确 SUDEP 定义的病例。根据爱尔兰共和国 2019 年的人口数量和已知的爱尔兰癫痫发病率，计算出 SUDEP 的发病率。据估计，整个癫痫人群中 SUDEP 的发病率为 0.7/1000(0.46 - 0.94) 人年。这可能是一个保守的估计。男性患者多于女性患者，大多数患者被发现死于家中。只有 52% 的病例在死亡证明中提及 SUDEP。这项工作表明，尽管有一定的局限性，但询问验尸记录是监测癫痫死亡率的有效方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Seizure-European Journal of Epilepsy 医学-临床神经学

CiteScore

5.60

自引率

6.70%

发文量

231

审稿时长

34 days

期刊介绍： Seizure - European Journal of Epilepsy is an international journal owned by Epilepsy Action (the largest member led epilepsy organisation in the UK). It provides a forum for papers on all topics related to epilepsy and seizure disorders.