Evaluation of the Importance of Capsule Transparency in Dry Powder Inhalation Devices.

IF 4.4 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Rocío Reinoso Arija, Rosario Ruiz-Serrano de la Espada, Mª Dolores Núñez Ollero, Laura Carrasco Hernandez, Esther Quintana Gallego, Jose Luis López-Campos
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引用次数: 0

Abstract

The aim of this work is to test whether the use of a transparent capsule affects the residual capsule weight after inhalation as a surrogate of the inhaled delivered dose for patients with non-reversible chronic airway disease. Researchers conducted an observational cross-sectional study with patients using a single-dose dry powder inhaler. The weight of the capsule was measured with a precision microbalance before and after inhalation. Ninety-one patients were included, of whom 63 (69.2%) used a transparent capsule. Inhalation with a transparent capsule achieved a weight decrease of 30.1% vs 8.6% for devices with an opaque capsule (P <0.001). These data reinforce the need to provide patients with mechanisms that verify the correct inhalation technique.

评估干粉吸入器中胶囊透明度的重要性。
这项工作的目的是测试使用透明胶囊是否会影响吸入后的残余胶囊重量,以此作为非可逆性慢性气道疾病患者吸入输送剂量的替代物。研究人员对使用单剂量干粉吸入器的患者进行了一项横断面观察研究。使用精密微量天平测量了吸入前后胶囊的重量。研究共纳入 91 名患者,其中 63 人(69.2%)使用透明胶囊。使用透明胶囊吸入时的重量减少了 30.1%,而使用不透明胶囊吸入时的重量减少了 8.6%(P
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来源期刊
Annals of Family Medicine
Annals of Family Medicine 医学-医学:内科
CiteScore
3.70
自引率
4.50%
发文量
142
审稿时长
6-12 weeks
期刊介绍: The Annals of Family Medicine is a peer-reviewed research journal to meet the needs of scientists, practitioners, policymakers, and the patients and communities they serve.
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