Morphea Associated with Adalimumab Treatment: The Role of TNF-α in Inhibition of Fibrosis.

Skinmed Pub Date : 2024-09-17 eCollection Date: 2024-01-01
Tamara Gracia-Cazaña, Victoria Fuentelsaz, Alba Navarro-Bielsa, Emilio Giner-Serret, Francisco Javier García-Latasa
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Abstract

Anti-tumor necrosis factor alpha (anti-TNF-α) comprises a group of drugs that inhibit the action of cytokine TNF-α, and are used to treat diseases mainly caused by this cytokine. An increase in cutaneous adverse events has been observed with similar anti-TNF biologic treatments frequently used in clinical practice.

与阿达木单抗治疗相关的斑秃:TNF-α 在抑制纤维化中的作用
抗肿瘤坏死因子α(anti-TNF-α)是一组抑制细胞因子 TNF-α 作用的药物,主要用于治疗由该细胞因子引起的疾病。临床上经常使用的类似抗肿瘤坏死因子的生物治疗方法已被观察到皮肤不良事件有所增加。
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