[Bipolar disorders and multiple etiologies : a link with attachment disorders ?]

Revue medicale de Liege Pub Date : 2024-09-01
Jean-Benoît Désert, Jean-Marc Triffaux
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引用次数: 0

Abstract

Bipolar disorders (BD) bring together different forms of mood disorders, characterized by the occurrence of depressive, manic, hypomanic and/or mixed episodes. They are recognized as the seventh cause of disability per year of life among 15 to 44 year old people by the World Health Organization (WHO). It is therefore a frequently encountered pathology. On the etiological level, the avenues currently accepted concerning BD are multiple, yet they still remain at the hypothesis stage. Each of these avenues therefore has therapeutic potential. It therefore seems interesting to address the different major hypotheses existing to date on the etiological level. We will first describe BD from historical, nosological and epidemiological points of view. We will then develop the genetic etiological aspects and the neural aspects through brain imaging research. Finally, we will propose a reflection on the specific relational etiology and the avenues of research that result from it.

[躁郁症和多重病因:与依恋障碍的联系?]
双相情感障碍(BD)是不同形式的情绪障碍的总称,其特征是抑郁、躁狂、躁郁和/或混合发作。世界卫生组织(WHO)认为,双相情感障碍是造成 15 至 44 岁人群每年残疾的第七大原因。因此,这是一种经常遇到的病症。在病因学层面,目前公认的有关 BD 的途径有多种,但仍停留在假设阶段。因此,这些途径中的每一种都具有治疗潜力。因此,我们有必要讨论一下迄今为止在病因学层面存在的各种主要假说。首先,我们将从历史学、病理学和流行病学的角度来描述 BD。然后,我们将从遗传学病因学方面和脑成像研究的神经学方面进行阐述。最后,我们将对特定的关系病因学和由此产生的研究途径进行反思。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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CiteScore
0.60
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