Vanishing Act: A Case Report of Missing Breast Tumour Marker.

IF 1 Q3 MEDICINE, GENERAL & INTERNAL
Cureus Pub Date : 2024-09-19 eCollection Date: 2024-09-01 DOI:10.7759/cureus.69737
Shaleene Subramaniam, Anushya Vijayananthan, Kartini Rahmat
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引用次数: 0

Abstract

Breast tissue markers are essential in localising tumours post-neoadjuvant chemotherapy prior to breast-conserving surgery. However, due to the advancement in neoadjuvant therapies, greater efficacy in reducing tumour size increases the possibility of marker migration, potentially compromising surgical outcomes. We report a case of a 34-year-old woman with left breast invasive carcinoma, where the tissue marker, placed under ultrasound guidance before chemotherapy, migrated and was undetectable after eight chemotherapy cycles. The delay in surgery was resolved by identifying the marker in the left pectoral muscle using CT, though proximity to the lung prevented hook wire placement. Proposed migration mechanisms include the "accordion effect" and haematoma-induced displacement, highlighting the dynamic nature of breast tissue. Various imaging modalities, such as mammography, ultrasound, and CT, have proven helpful for marker localisation. This case underscores the need for a deeper understanding of tissue dynamics and emphasises interdisciplinary communication to adapt treatment strategies. As medical knowledge continues to evolve, insights are needed to refine best practices in breast cancer management and radiological interventions.

消失的行为:乳腺肿瘤标记物缺失的病例报告。
保乳手术前,乳腺组织标记物对新辅助化疗后肿瘤的定位至关重要。然而,由于新辅助疗法的进步,缩小肿瘤体积的效果越来越好,这就增加了标记物迁移的可能性,可能会影响手术效果。我们报告了一例 34 岁女性左侧乳腺浸润癌患者的病例,化疗前在超声引导下放置的组织标记物发生了迁移,八个化疗周期后无法检测到。虽然因靠近肺部而无法放置钩丝,但通过 CT 在左胸肌中发现了标记物,从而解决了手术延迟的问题。提出的移位机制包括 "手风琴效应 "和血肿引起的移位,凸显了乳腺组织的动态特性。事实证明,乳腺 X 线照相、超声波和 CT 等多种成像模式有助于标记物的定位。该病例强调了深入了解组织动态的必要性,并强调了跨学科交流以调整治疗策略的重要性。随着医学知识的不断发展,我们需要深入了解乳腺癌管理和放射干预的最佳实践。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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