Comparison of dimensions and functional features of mitral and tricuspid annuli in the same healthy adults: insights from the three-dimensional speckle-tracking echocardiographic MAGYAR-Healthy Study.
IF 2.9 2区 医学Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
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引用次数: 0
Abstract
Background: Evaluation of mitral (MA) and tricuspid annuli (TA) in the same healthy subject in a non-invasive way in real-life clinical settings makes an opportunity to compare their dimensions and derived functional properties. The purpose of the present cohort study was to investigate whether there are any differences in the three-dimensional speckle-tracking echocardiography- (3DSTE-) measured size and derived functional characteristics of the MA and TA in the same healthy adults.
Methods: The study comprised 248 healthy adults, in which 3DSTE was performed to determine MA and TA dimensions and functional properties. Due to insufficient image quality, 89 cases were excluded, therefore the remaining population consisted of 159 subjects (age: 35.6±12.9 years, 76 males). Subjects were enrolled on a voluntary basis consecutively between January 2011 and November 2017 in the outpatient clinic of the tertiary cardiology center at the Department of Medicine, University of Szeged, Hungary. Data were analyzed by Student's t-test, analysis of variance (ANOVA) test, Fischer's exact test, Pearsons' correlations, interclass correlations and Bland-Altman tests.
Results: Same-side MA/TA end-diastolic annular dilation is associated with simultaneous MA/TA end-systolic dilation and vice versa. MA dilation in end-diastole and end-systole results in MA functional improvement/deterioration. Dilation of end-diastolic TA dimensions does not obviously entail differences in TA function. However, similar to MA, more dilated TA in end-systole is associated with impaired TA function. Dilated MA dimensions (end-diastolic MA area: 4.31±0.62 vs. 10.89±1.18 cm2, P<0.05) are not obviously associated with dilated end-diastolic TA dimensions (area: 7.05±1.42 vs. 7.81±1.48 cm2, P=ns) and functional improvement/impairment (fractional area change: 27.5%±10.8% vs. 25.2%±10.6%, P=ns).
Conclusions: Dilation of MA and TA is associated with different contralateral responses in morphology and function.
背景：在真实的临床环境中以无创方式对同一健康受试者的二尖瓣环（MA）和三尖瓣环（TA）进行评估，为比较它们的尺寸和衍生功能特性提供了机会。本队列研究旨在探讨三维斑点追踪超声心动图（3DSTE）测量的同一健康成人 MA 和 TA 的尺寸和衍生功能特性是否存在差异：研究对象包括 248 名健康成年人，通过三维斑点追踪超声心动图确定 MA 和 TA 的尺寸和功能特性。由于图像质量不佳，89 个病例被排除在外，因此剩下的研究对象包括 159 名受试者（年龄：35.6±12.9 岁，76 名男性）。受试者于2011年1月至2017年11月期间在匈牙利塞格德大学医学系三级心脏病学中心门诊部自愿连续注册。数据分析采用学生 t 检验、方差分析（ANOVA）检验、费舍尔精确检验、Pearsons 相关性、类间相关性和 Bland-Altman 检验：结果：同侧 MA/TA 舒张末期瓣环扩张与 MA/TA 收缩末期同时扩张相关，反之亦然。MA 舒张末期和收缩末期扩张会导致 MA 功能改善/恶化。舒张末期 TA 尺寸的扩张并不明显导致 TA 功能的差异。然而，与 MA 相似，舒张末期 TA 更多扩张与 TA 功能受损有关。扩张的MA尺寸（舒张末期MA面积：4.31±0.62 vs 4.31±0.624.31±0.62 vs. 10.89±1.18 cm2，Pvs. 7.81±1.48 cm2，P=ns）和功能改善/受损（分数面积变化：27.5%±10.8% vs. 25.2%±10.6%，P=ns）：结论：MA 和 TA 的扩张与对侧形态和功能的不同反应有关。
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