Arterial stiffness is associated with new-onset chronic kidney disease.

IF 2.1 4区 医学 Q3 PERIPHERAL VASCULAR DISEASE
Kangbo Li, Qi Qi, Xinyi Li, Liying Tian, Liyan Wang, Shouling Wu, Quanle Han
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引用次数: 0

Abstract

Background: A potential independent association between arterial stiffness (AS) and the development of new-onset chronic kidney disease (CKD) has not been thoroughly examined. Patients and methods: A total of 6929 participants were collected from the Kailuan study. All participants were free of CKD at the baseline. The participants were divided into four groups based on their brachial-ankle pulse wave velocity (baPWV) values. Cox regression models were used to analyze the relationship between baPWV values and the risk of new-onset CKD. Results: Over the course of a 10.06-year follow-up period, a total of 962 cases of new-onset CKD were documented. Cox proportional hazards analyses showed that a higher baPWV quartile was linked to an increased risk of new-onset CKD. Conclusions: Brachial-ankle pulse wave velocity has a strong correlation with the development of new-onset CKD. Therefore, baPWV can be considered an innovative indicator for predicting the occurrence of new-onset CKD.

动脉僵化与新发慢性肾病有关。
背景:动脉僵化(AS)与新发慢性肾脏病(CKD)发病之间的潜在独立关联尚未得到深入研究。患者和方法:开滦研究共收集了 6929 名参与者。所有参与者在基线时均无慢性肾脏病。根据肱踝关节脉搏波速度(baPWV)值将参与者分为四组。采用 Cox 回归模型分析了 baPWV 值与新发 CKD 风险之间的关系。结果显示在长达 10.06 年的随访期间,共记录了 962 例新发 CKD 病例。Cox 比例危险度分析表明,baPWV 四分位数越高,新发 CKD 的风险越高。结论是肱踝关节脉搏波速度与新发慢性肾脏病的发生密切相关。因此,baPWV 可被视为预测新发 CKD 的创新指标。
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来源期刊
CiteScore
3.90
自引率
11.10%
发文量
61
审稿时长
1 months
期刊介绍: Vasa is the European journal of vascular medicine. It is the official organ of the German, Swiss, and Slovenian Societies of Angiology. The journal publishes original research articles, case reports and reviews on vascular biology, epidemiology, prevention, diagnosis, medical treatment and interventions for diseases of the arterial circulation, in the field of phlebology and lymphology including the microcirculation, except the cardiac circulation. Vasa combines basic science with clinical medicine making it relevant to all physicians interested in the whole vascular field.
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