Ten-Year Incidence of Sarcopenia in a Population-Based Cohort: Results from the Research on Osteoarthritis/Osteoporosis Against Disability Study

IF 4.2 2区医学 Q2 GERIATRICS & GERONTOLOGY

Journal of the American Medical Directors Association Pub Date : 2024-09-14 DOI:10.1016/j.jamda.2024.105263

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引用次数: 0

Abstract

Objectives

To investigate the prevalence and incidence rates of sarcopenia in Japanese community-dwelling people according to the criteria of the Asian Working Group for Sarcopenia 2019 recommendations, using a large-scale population-based cohort over a 10-year follow-up period.

Design

Prospective cohort study.

Setting and Participants

This study was conducted using data from the Research on Osteoarthritis/Osteoporosis Against Disability (ROAD) study. In total, 1551 participants (521 men and 1030 women; mean age, 65.8 years) from the second ROAD survey (2008–2-10) were included in this study.

Methods

The participants from the second survey were followed-up at 4, 7, and 10 years. Skeletal muscle mass, handgrip strength, and walking speed were assessed. Sarcopenia was defined according to the Asian Working Group for Sarcopenia 2019 criteria. The incidence of sarcopenia was calculated using the person-year method. Cox proportional hazard model was used to assess risk factors for incident sarcopenia.

Results

The prevalence of sarcopenia was 8.1% (8.8% in men and 7.7% in women), and the prevalence of severe sarcopenia was 2.9% (2.7% in men and 3.1% in women). The incidence rates of sarcopenia were 17.8 per 1000 and 14.5 per 1000 person-years in men and women, respectively. Additionally, the incidence rates of severe sarcopenia were 6.4 per 1000 and 4.2 per 1000 person-years in men and women, respectively. The significant risk factors for the incidence of sarcopenia were age [+1 year; hazard ratio (HR), 1.10; 95% CI, 1.08-1.12] and body mass index (−1 kg/m²; HR, 1.27; 95% CI, 1.20-1.35). The significant risk factors for the incidence of severe sarcopenia were age (+1 year; HR, 1.18; 95% CI, 1.14-1.22) and body mass index (−1 kg/m²; HR, 1.21; 95% CI, 1.10-1.33).

Conclusions and Implications

The prevalence and incidence rates of sarcopenia in Japan were clarified in this study.

查看原文本刊更多论文

以人口为基础的队列中的肌肉疏松症十年发病率：ROAD 研究的结果。

目的根据 "亚洲肌少症工作组 "2019年建议的标准，通过一项为期10年的大规模人群队列随访，调查日本社区居民的肌少症患病率和发病率：前瞻性队列研究：本研究使用了骨关节炎/骨质疏松症致残研究（ROAD）的数据。本研究共纳入了 ROAD 第二次调查（2008-2-10）中的 1551 名参与者（男性 521 人，女性 1030 人；平均年龄 65.8 岁）：方法：对第二次调查的参与者进行了 4 年、7 年和 10 年的随访。对骨骼肌质量、手握力和步行速度进行了评估。根据 "亚洲肌少症工作组 2019 年标准 "对 "肌少症 "进行定义。肌少症的发病率采用人年法计算。采用Cox比例危险模型评估肌肉疏松症发病的风险因素：结果：肌肉疏松症的发病率为8.1%（男性为8.8%，女性为7.7%），严重肌肉疏松症的发病率为2.9%（男性为2.7%，女性为3.1%）。男性和女性的肌肉疏松症发病率分别为每 1000 人年 17.8 例和 14.5 例。此外，严重肌肉疏松症的发病率在男性和女性中分别为每千人年 6.4 例和 4.2 例。肌少症发病率的重要风险因素是年龄（+1 岁；危险比 [HR]，1.10；95% CI，1.08-1.12）和体重指数（-1 kg/m2；HR，1.27；95% CI，1.20-1.35）。严重肌肉疏松症发病率的重要风险因素是年龄（+1 岁；HR，1.18；95% CI，1.14-1.22）和体重指数（-1 kg/m2；HR，1.21；95% CI，1.10-1.33）：本研究明确了日本肌肉疏松症的流行率和发病率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of the American Medical Directors Association 医学-老年医学

CiteScore

11.10

自引率

6.60%

发文量

472

审稿时长

44 days

期刊介绍： JAMDA, the official journal of AMDA - The Society for Post-Acute and Long-Term Care Medicine, is a leading peer-reviewed publication that offers practical information and research geared towards healthcare professionals in the post-acute and long-term care fields. It is also a valuable resource for policy-makers, organizational leaders, educators, and advocates. The journal provides essential information for various healthcare professionals such as medical directors, attending physicians, nurses, consultant pharmacists, geriatric psychiatrists, nurse practitioners, physician assistants, physical and occupational therapists, social workers, and others involved in providing, overseeing, and promoting quality