Fair expectations for patients undergoing preimplantation genetic testing for monogenic disorders: aneuploidy no less of an obstacle.

IF 6.6 1区医学 Q1 OBSTETRICS & GYNECOLOGY

Fertility and sterility Pub Date : 2024-12-01 Epub Date: 2024-09-21 DOI:10.1016/j.fertnstert.2024.09.033

Stephanie Willson, Emily Mounts, Marie Werner

引用次数: 0

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对 PGT-M 患者的合理期望：非整倍体并非障碍。

单基因遗传病胚胎植入前基因检测（PGT-M）是本领域的一项重大进展，为面临遗传病可能传播的家庭提供了一种强有力的降低风险策略。这一过程为患者提供了宝贵的胚胎选择工具，随着遗传诊断和携带者身份得到更广泛的认可，使用率也在稳步上升。然而，与胚胎植入前非整倍体基因检测（PGT-A）一样，选择机会增加的注意事项是可用于移植的胚胎随之减少。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Fertility and sterility 医学-妇产科学

CiteScore

11.30

自引率

6.00%

发文量

1446

审稿时长

31 days

期刊介绍： Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.