Analysis of IgE level influencing factors of common allergens for allergic rhinitis in northeastern China.

IF 2.2 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

Clinics Pub Date : 2024-09-11 eCollection Date: 2024-01-01 DOI:10.1016/j.clinsp.2024.100495

Yanling Chu, Ai-Hui Yan

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引用次数: 0

Abstract

Objectives: This thesis aims to provide patients with a preventive and therapeutic basis by analyzing IgE level influencing factors of common allergens for Allergic Rhinitis (AR).

Method: Multiple linear regression analysis is made upon questionnaires among 749 cases of AR patients that are divided into 5 age-based groups. Perform serum-specific IgE content testing on patients.

Results: Cockroach being an allergen, AR patients' IgE Level is influenced by allergic history, home-raised plants and animals. For AR patients with mugwort as an allergen, allergy and asthma history could increase IgE level, respectively, β = 4.291 and β = 4.364. If the allergen turns out to be peanut, allergic history would increase the IgE level (β = 0.171), however, the level would be lower in female patients compared with male patients (β = -0.078). For patients with egg as an allergen, allergic history, home-raised plants and animals (pets) would all affect the IgE level, respectively, β = 0.182, β = 0.118 and β = -0.101.

Conclusions: IgE level varies according to allergic history, home-raised plants & animals, gender, furniture renewal, asthma, and ages for patients with different allergens including cockroach, mold, mugwort, peanut, egg and crab. For each kind of allergen, the IgE levels react differently to different influencing factors, thus requiring a thorough analysis of each AR patient's allergen and allergenic factors.

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中国东北地区过敏性鼻炎常见过敏原的 IgE 水平影响因素分析

目的：本论文旨在通过分析过敏性鼻炎（AR）常见过敏原的 IgE 水平影响因素，为患者提供预防和治疗依据：本论文旨在通过分析过敏性鼻炎（AR）常见过敏原的 IgE 水平影响因素，为患者提供预防和治疗依据：方法：对749例AR患者的问卷进行多元线性回归分析，按年龄分为5组。对患者进行血清特异性 IgE 含量检测：结果：蟑螂是一种过敏原，AR 患者的 IgE 水平受过敏史、家庭饲养的植物和动物的影响。对于以艾草为过敏原的 AR 患者，过敏史和哮喘史会增加 IgE 水平，分别为 β = 4.291 和 β = 4.364。如果过敏原是花生，过敏史会增加 IgE 水平（β = 0.171），但女性患者的 IgE 水平低于男性患者（β = -0.078）。对于以鸡蛋为过敏原的患者，过敏史、家庭饲养的植物和动物（宠物）都会影响 IgE 水平，分别为 β = 0.182、β = 0.118 和 β = -0.101：对于蟑螂、霉菌、艾草、花生、鸡蛋和螃蟹等不同过敏原的患者，其 IgE 水平因过敏史、家庭饲养动植物、性别、家具更新、哮喘和年龄而异。对于每种过敏原，IgE 水平对不同影响因素的反应也不同，因此需要对每位 AR 患者的过敏原和致敏因素进行全面分析。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinics 医学-医学：内科

CiteScore

4.10

自引率

3.70%

发文量

129

审稿时长

52 days

期刊介绍： CLINICS is an electronic journal that publishes peer-reviewed articles in continuous flow, of interest to clinicians and researchers in the medical sciences. CLINICS complies with the policies of funding agencies which request or require deposition of the published articles that they fund into publicly available databases. CLINICS supports the position of the International Committee of Medical Journal Editors (ICMJE) on trial registration.