Dynamics of Splenic Transient Elastography in Patients With Alcohol Use Disorder.

IF 3 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Clinical and Translational Gastroenterology Pub Date : 2024-09-23 DOI:10.14309/ctg.0000000000000770

Mian B Khalid, Hanna L Blaney, Anusha Vittal, Alexander H Yang, Bilal A Asif, Natasha Kamal, Elizabeth C Wright, Chris Koh, David George, David Goldman, Yvonne Horneffer, Nancy Diazgranados, Theo Heller

引用次数: 0

Abstract

Introduction: Splenic stiffness (SS) measurement (SSM) is an evolving noninvasive assessment to evaluate portal hypertension. Studies with respect to SSM in patients with alcohol use disorder are limited.

Methods: We studied patients seeking treatment for alcohol use disorder in an inpatient treatment protocol at the National Institutes of Health and parsed SSM into 3 groups based on degree of change.

Results: The improved SS group had statistically higher initial SSM and a nonstatistically increased liver stiffness measurement compared with others.

Discussion: SS is dynamic in a subset of patients immediately after alcohol cessation, and improved SS is associated with a normalization of platelet count.

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酒精使用障碍患者脾脏瞬态弹性成像的动态变化。

简介：脾脏僵硬度测量（SSM）是一种不断发展的评估门静脉高压的非侵入性评估方法。有关酒精使用障碍（AUD）患者脾脏硬度测量的研究非常有限：我们研究了在美国国立卫生研究院住院治疗方案中寻求治疗的 AUD 患者，并根据变化程度将 SSM 分成 3 组：结果：与其他组别相比，"改善 "SSM组的初始SSM在统计学上更高，肝脏硬度测量（LSM）在统计学上没有增加：讨论：部分患者在戒酒后会立即出现 SS 动态变化，SSM 的改善与血小板计数的正常化有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical and Translational Gastroenterology GASTROENTEROLOGY & HEPATOLOGY-

CiteScore

7.00

自引率

0.00%

发文量

114

审稿时长

16 weeks

期刊介绍： Clinical and Translational Gastroenterology (CTG), published on behalf of the American College of Gastroenterology (ACG), is a peer-reviewed open access online journal dedicated to innovative clinical work in the field of gastroenterology and hepatology. CTG hopes to fulfill an unmet need for clinicians and scientists by welcoming novel cohort studies, early-phase clinical trials, qualitative and quantitative epidemiologic research, hypothesis-generating research, studies of novel mechanisms and methodologies including public health interventions, and integration of approaches across organs and disciplines. CTG also welcomes hypothesis-generating small studies, methods papers, and translational research with clear applications to human physiology or disease. Colon and small bowel Endoscopy and novel diagnostics Esophagus Functional GI disorders Immunology of the GI tract Microbiology of the GI tract Inflammatory bowel disease Pancreas and biliary tract Liver Pathology Pediatrics Preventative medicine Nutrition/obesity Stomach.