Precise prediction of size of a foldable capsular vitreous body via computerized three-dimensional ocular reconstruction in severe retinal detachment.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-09-20 DOI:10.1186/s12886-024-03646-9

Chongde Long, Qianying Gao, Shenwen Liu, Yan Chen, Huping Song, Jinguo Yu, Bingsheng Lou, Zhaohui Yuan, Yongxin Zheng, Liuxueying Zhong, Siqi Qiao, Xiangda Meng, Yuanyuan Liu, Yingyu Wang, Yuanyuan Liu, Xiaofeng Lin, Hua Yan

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Abstract

Background: This study aimed to precisely predict the size and silicone oil injection of a foldable capsular vitreous body (FCVB) via computerized three-dimensional (3D) ocular reconstruction in the treatment of severe retinal detachment in China.

Methods: The 3D software Unigraphics NX was applied to determine the volume of the inner cavity with 16-30 mm axial length, assigning the anterior and posterior chambers, the FCVB sizes, and the silicone oil injection volume, and modeling the data between the axial length and the FCVB size. In clinical practice, IOL Master was applied to accurately measure the axial length of the contralateral healthy eye to anchor the anterior-posterior and horizontal diameters of the operated eye in horizontal position CT, and compared with the model to recommend the FCVB size and silicone oil amount, and the clinical effect was validated in cases across five hospitals in China.

Results: For the axial length of 16-30 mm, the volume of the inner cavity is 1.2 ml-8.4 ml. FCVB size and silicone oil volume were recommended based on this volume of the inner cavity. Of 253 cases, we noted 11 cases implanted with AV-10P and 1.05 ± 0.21 ml of silicone oil, 41 with AV-12P and 1.58 ± 0.18 ml of silicone oil, 163 with AV-13.5P and 2.48 ± 0.29 ml of silicone oil, 31 with AV-15P and 3.57 ± 0.39 ml of silicone oil, and 7 with AV-17P and 5.71 ± 0.81 ml of silicone oil. There was no significant difference in postoperative visual acuity scores compared with preoperative (P = 0.097), postoperative IOP(10.29 ± 0.57mmHg)was slightly higher than preoperative IOP (9.76 ± 0.48 mmHg), but there was still no statistically significant difference between the two comparisons (P = 0.405).

Conclusion: Three-dimensional reconstruction prediction is a good solution for eyeballs with obvious individualized changes in severe retinal detachment, and this method helps doctors standardize FCVB size selection and the silicone oil amount for patients.

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通过计算机三维眼部重建精确预测严重视网膜脱离患者的可折叠囊状玻璃体大小。

背景：本研究旨在通过计算机三维（3D）眼部重建技术精确预测可折叠囊玻璃体（FCVB）的大小和硅油注入量，用于中国重度视网膜脱离的治疗：应用三维软件Unigraphics NX确定轴长为16-30 mm的内腔体积，分配前后腔、FCVB尺寸和硅油注入量，并建立轴长与FCVB尺寸之间的数据模型。在临床实践中，应用IOL Master精确测量对侧健康眼的轴长，在水平位CT上锚定手术眼的前后径和水平径，并与模型比较，推荐FCVB大小和硅油量，在国内五家医院的病例中验证了临床效果：结果：轴向长度为16-30 mm时，内腔容积为1.2 ml-8.4 ml。根据这一内腔容积推荐了 FCVB 的尺寸和硅油量。在 253 个病例中，我们注意到有 11 例植入了 AV-10P 和 1.05 ± 0.21 毫升硅油，41 例植入了 AV-12P 和 1.58 ± 0.18 毫升硅油，163 例植入了 AV-13.5P 和 2.48 ± 0.29 毫升硅油，31 例植入了 AV-15P 和 3.57 ± 0.39 毫升硅油，7 例植入了 AV-17P 和 5.71 ± 0.81 毫升硅油。术后视力评分与术前相比无明显差异（P = 0.097），术后眼压（10.29 ± 0.57 mmHg）略高于术前眼压（9.76 ± 0.48 mmHg），但两组比较仍无统计学差异（P = 0.405）：结论：三维重建预测法可以很好地解决严重视网膜脱离患者眼球个体化变化明显的问题，有助于医生为患者规范选择FCVB尺寸和硅油用量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.