Anti-oxidant, anti-inflammatory and antimicrobial activity of aqueous extract from acerola and amla.

IF 1.9

Bioinformation Pub Date : 2024-07-31 eCollection Date: 2024-01-01 DOI:10.6026/973206300200765

Chellathurai Burnice Nalina Kumari, Namasivayam Ambalavanan, Shanmugam Rajesh Kumar, Jaideep Mahendra, Uma Sudhakar

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Abstract

Amla, scientifically known as emblica officinalis and Acerola (malphigian emarginata) both are Vitamin C fruits possess varied medicinal properties being used for preventive disease health management strategies. Therefore, it is of interest to explore the antioxidant, anti-inflammatory, antibacterial, and cytotoxic properties of aqueous extracts from Acerola and Amla. Hence, the anti-inflammatory activity of Acerola and amla was assessed using the bovine serum albumin denaturation assay (BSA Assay), antioxidant properties were compared using DPPH (2,2-diphenyl-1-picrylhydrazyl) assay. Both extracts antibacterial activities were evaluated through the agar well diffusion technique against oral pathogens and Brine shrimp lethality assay for cytotoxicity. The current research sheds light on natural remedies for oxidative stress-related diseases, inflammatory conditions and bacterial infections, offering promising avenues for disease management and preventive healthcare strategies especially in the treatment of oral health diseases like periodontitis.

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针叶树和杏树水提取物的抗氧化、抗炎和抗菌活性。

阿木拉（学名：emblica officinalis）和金银花（malphigian emarginata）都是维生素 C 水果，具有多种药用特性，可用于预防疾病的健康管理策略。因此，我们有兴趣探索从金银花和阿姆拉中提取的水提取物的抗氧化、抗炎、抗菌和细胞毒性特性。因此，采用牛血清白蛋白变性测定法（BSA Assay）评估了针叶树和杏树的抗炎活性，并采用 DPPH（2,2-二苯基-1-苦基肼）测定法比较了其抗氧化特性。通过琼脂井扩散技术评估了两种提取物对口腔病原体的抗菌活性，并通过盐水虾致死试验评估了细胞毒性。目前的研究揭示了治疗氧化应激相关疾病、炎症和细菌感染的天然疗法，为疾病管理和预防保健策略，尤其是治疗牙周炎等口腔疾病提供了很好的途径。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Bioinformation MATHEMATICAL & COMPUTATIONAL BIOLOGY-

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