An evaluation of the effect of the use of platelet-rich fibrin on tonsillectomy results

IF 2.5 4区医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL

Advances in medical sciences Pub Date : 2024-09-01 DOI:10.1016/j.advms.2024.09.004

Aslıhan Oflaz Çapar, Emre Solguntekin, Kerem Kökoğlu, Mehmet Ilhan Şahin

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引用次数: 0

Abstract

Purpose

The aim of this study was to investigate the effect of liquid platelet-rich fibrin (PRF) during tonsillectomy on postoperative results.

Patients and methods

This study included 41 patients who underwent tonsillectomy between April 2022 and January 2023. Liquid-PRF at a dose of 1 cc was injected to three different points of one of the tonsil fossae, selected at random intraoperatively. The same amount of physiological saline was injected to the symmetrical points on the opposite tonsil fossa using the same size injector. Pain, wound healing, and bleeding were evaluated on postoperative days 1, 7, and 14. The data of both sides were compared statistically as the study and control sides.

Results

The pain scores were the highest for both sides on postoperative day 1, and gradually decreased in the following days, with no significant difference determined between the sides (p > 0.05). Wound healing rates in the 1st week and 2 nd week were similar for both sides. Although there were more patients who have 100 % epithelization in the PRF group on the postoperative day 14, the difference between the groups was not statistically significant (p > 0.05).

Conclusions

The injection of PRF following tonsillectomy had no significant effect on postoperative pain, wound healing, or bleeding.

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评估使用富血小板纤维蛋白对扁桃体切除术效果的影响。

目的：本研究旨在探讨扁桃体切除术中液态富血小板纤维蛋白（PRF）对术后效果的影响：本研究纳入了在 2022 年 4 月至 2023 年 1 月期间接受扁桃体切除术的 41 名患者。在术中随机选择扁桃体窝的三个不同点注射 1cc 剂量的液体-PRF。使用相同大小的注射器，在对侧扁桃体窝的对称点注射相同剂量的生理盐水。术后第 1、7 和 14 天对疼痛、伤口愈合和出血情况进行评估。将两侧的数据作为研究侧和对照侧进行统计比较：结果：术后第 1 天两侧疼痛评分最高，随后几天逐渐降低，两侧疼痛评分无明显差异（P>0.05）。第 1 周和第 2 周的伤口愈合率两侧相似。虽然术后第 14 天 PRF 组上皮化生率达 100% 的患者较多，但组间差异无统计学意义（P>0.05）：扁桃体切除术后注射 PRF 对术后疼痛、伤口愈合和出血无明显影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Advances in medical sciences 医学-医学：研究与实验

CiteScore

5.00

自引率

0.00%

发文量

审稿时长

25 days

期刊介绍： Advances in Medical Sciences is an international, peer-reviewed journal that welcomes original research articles and reviews on current advances in life sciences, preclinical and clinical medicine, and related disciplines. The Journal’s primary aim is to make every effort to contribute to progress in medical sciences. The strive is to bridge laboratory and clinical settings with cutting edge research findings and new developments. Advances in Medical Sciences publishes articles which bring novel insights into diagnostic and molecular imaging, offering essential prior knowledge for diagnosis and treatment indispensable in all areas of medical sciences. It also publishes articles on pathological sciences giving foundation knowledge on the overall study of human diseases. Through its publications Advances in Medical Sciences also stresses the importance of pharmaceutical sciences as a rapidly and ever expanding area of research on drug design, development, action and evaluation contributing significantly to a variety of scientific disciplines. The journal welcomes submissions from the following disciplines: General and internal medicine, Cancer research, Genetics, Endocrinology, Gastroenterology, Cardiology and Cardiovascular Medicine, Immunology and Allergy, Pathology and Forensic Medicine, Cell and molecular Biology, Haematology, Biochemistry, Clinical and Experimental Pathology.