Synthesis of new chiral arylsulfonamides based on carane amino alcohols
IF 1.7
4区 化学
Q3 CHEMISTRY, MULTIDISCIPLINARY
引用次数: 0
Abstract
New optically active arylsulfonamides, including carane-containing streptocide analogs, were synthesized by the reaction of carane amino alcohols with tosyl- and N-acetylsulfanilyl chlorides. Sulfonamide, which was prepared based on (–)-4β-amino-3α-hydroxy-cis-carane, was studied by X-ray diffraction. The synthesized sulfonamides and the starting amino alcohols were evaluated for antimicrobial activity.
基于甲烷氨基醇的新型手性芳基磺酰胺的合成
通过卡烷氨基醇与对甲苯磺酰氯和 N-乙酰基磺酰氯的反应，合成了新的光学活性芳基磺酰胺，包括含卡烷的链烷类似物。通过 X 射线衍射研究了以 (-)-4β- 氨基-3α-羟基顺式卡烷为基础制备的磺酰胺。对合成的磺酰胺和起始氨基醇进行了抗菌活性评估。
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来源期刊
Russian Chemical Bulletin
化学-化学综合
CiteScore
2.70
自引率
47.10%
发文量
257
审稿时长
3-8 weeks
期刊介绍：
Publishing nearly 500 original articles a year, by leading Scientists from Russia and throughout the world, Russian Chemical Bulletin is a prominent international journal. The coverage of the journal spans practically all areas of fundamental chemical research and is presented in five sections:
General and Inorganic Chemistry;
Physical Chemistry;
Organic Chemistry;
Organometallic Chemistry;
Chemistry of Natural Compounds and Bioorganic Chemistry.
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