Hydrolytic opening of the imidazole ring under action of acetylenecarboxylic acid derivatives

IF 1.7 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Russian Chemical Bulletin Pub Date : 2024-09-19 DOI:10.1007/s11172-024-4356-x

K. V. Belyaeva, L. P. Nikitina, A. V. Afonin, B. A. Trofimov

引用次数: 0

Abstract

A three-components regioselective synthesis of 3-[2-formamidovinyl(phenyl)amino]-acrylic acid based on an opening of the imidazole ring under the influence of acetylene carboxylic acids esters or cyanophenylacetylene in aqueous acetonitrile in up to 86% yields has been developed.

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乙炔羧酸衍生物作用下咪唑环的水解开口

在乙炔羧酸酯或氰基苯基乙炔的作用下，在乙腈水溶液中打开咪唑环，从而合成 3-[2-formamidovinyl(phenyl)amino]-丙烯酸的三组分区域选择性合成方法已经开发成功，收率高达 86%。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Russian Chemical Bulletin 化学-化学综合

CiteScore

2.70

自引率

47.10%

发文量

257

审稿时长

3-8 weeks

期刊介绍： Publishing nearly 500 original articles a year, by leading Scientists from Russia and throughout the world, Russian Chemical Bulletin is a prominent international journal. The coverage of the journal spans practically all areas of fundamental chemical research and is presented in five sections: General and Inorganic Chemistry; Physical Chemistry; Organic Chemistry; Organometallic Chemistry; Chemistry of Natural Compounds and Bioorganic Chemistry.